1.
J Pharm Pharmacol
; 36(8): 536-8, 1984 Aug.
Artigo
em Inglês
| MEDLINE
| ID: mdl-6148397
RESUMO
The dissolution behaviour of four commercial and two experimental formulations of frusemide tablets has been investigated using the USP rotating basket apparatus and pH 5.0 buffer at 37 degrees C as the test medium. There is a linear relationship between the percentage dissolution in 30 min and the bioavailability relative to an oral solution of frusemide over the bioavailability range 76-97%. Predicted bioavailabilities differed by no more than 2% from the measured values.