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1.
Exp Clin Psychopharmacol ; 30(5): 547-559, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34291988

RESUMO

A recent study of the impact of smoked cannabis on simulated driver behavior demonstrated a reduction in mean speed after smoked cannabis. Previous research identified an association between personality and individual differences and acute drug effects. The present study examined the impact of personality on the reduction in mean speed after smoking cannabis under single- and dual-task driving conditions originally reported by Brands et al. (2019). Sixty-one participants randomly assigned to the active drug condition completed a battery of self-report questionnaires measuring various personality constructs and subsequently operated a driving simulator before and 30 min after smoking a 12.5% Δ9-tetrahydrocannabinol (THC) cigarette. Linear regression modeling tested the influence of self-reported driving errors, lapses, and violations, driver vengeance, psychological distress, impulsivity, and sensation seeking on the reduction in speed after smoking cannabis. After adjusting for the influence of sex, blood THC concentration, and predrug mean speed, impulsivity was a significant predictor of change in speed under both single- (ß = -.45, t = -3.94, p < .001) and dual- (ß = -.35, t = -2.74, p = .008) task driving conditions after cannabis. Higher trait impulsivity was significantly associated with greater reductions in driving speed after cannabis use, which may reflect greater sensitivity to drug effects and a stronger compensatory response. Further multidisciplinary study, including neurochemical, genetic, and psychological components, would be beneficial in helping to better understand how impulsivity and other personality or individual differences may impact the effects of cannabis on driver behavior and performance. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Assuntos
Condução de Veículo , Cannabis , Alucinógenos , Fumar Maconha , Dronabinol/farmacologia , Alucinógenos/farmacologia , Humanos , Personalidade
2.
Drug Alcohol Depend ; 213: 108103, 2020 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-32559668

RESUMO

BACKGROUND: Existing studies of attention deficit/hyperactivity disorder (ADHD), conduct disorder (CD), and substance use or substance use disorders have produced mixed results, with some identifying a direct link between ADHD and general or disordered substance use and others suggesting that comorbid CD may explain this relationship. Insufficient research has addressed the issue, which is particularly relevant in the context of the opioid crisis. This study examined the association of probable ADHD and childhood CD with self-reported opioid use in a general-population sample. METHOD: The 2011-2013 cycles of the CAMH Monitor, a cross-sectional survey of adults (18+ years) from Ontario, Canada provided data from 6074 respondents. Binary logistic regressions were conducted of self-reported medical, non-medical, and any prescription opioid use in the previous 12 months, assessing demographic characteristics, perceived physical and mental health, and probable ADHD, childhood (before age 15 years) symptoms of CD, or their combination. RESULTS: Adjusting for potential covariates, probable ADHD alone was not associated with prescription opioid use. Childhood symptoms of CD significantly predicted non-medical use (OR = 2.10, 95% CI = 1.10, 4.03). ADHD and CD symptoms combined significantly predicted medical (OR = 3.27, 95% CI = 1.20, 8.91), non-medical (OR = 4.73, 95% CI = 1.05, 21.30), and any (OR = 3.02, 95% CI = 1.13, 8.11) prescription opioid use, although a low base rate of non-medical use may have negatively affected model fit. CONCLUSIONS: Previous findings relating ADHD to opioid use could be explained, in part, by the high rate of comorbidity between ADHD and CD. These data support prevention and treatment programs targeting individuals with comorbid ADHD and CD symptoms.

3.
Prev Sci ; 5(4): 253-66, 2004 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-15566051

RESUMO

After school programs (ASPs) are popular and receive substantial public funding. Aside from their child-care and supervision value, ASPs often provide youth development and skill-building activities that might reduce delinquent behavior. These possibilities and the observation that arrests for juvenile crime peak between 2 p.m. and 6 p.m. on school days have increased interest in the delinquency prevention potential of ASPs. This study examined effects of participation in ASPs conducted in Maryland during the 1999--2000 school year and the mechanism through which such programs may affect delinquent behavior. Results imply that participation reduced delinquent behavior for middle-school but not for elementary-school-aged youths. This reduction was not achieved by decreasing time spent unsupervised or by increasing involvement in constructive activities, but by increasing intentions not to use drugs and positive peer associations. Effects on these outcomes were strongest in programs that incorporated a high emphasis on social skills and character development.


Assuntos
Comportamento do Adolescente , Comportamento Infantil , Creches/normas , Delinquência Juvenil/prevenção & controle , Prevenção Primária/métodos , Serviços de Saúde Escolar/normas , Adolescente , Comportamento do Adolescente/psicologia , Criança , Comportamento Infantil/psicologia , Feminino , Humanos , Masculino , Maryland , Grupo Associado , Estudos Retrospectivos , Fatores de Risco , Assunção de Riscos , Inquéritos e Questionários , Fatores de Tempo
5.
In. White, Kerr L; Frenk, Julio; Ordoñez Carceller, Cosme; Paganini, José Maria; Starfield, Bárbara. Health services research: An anthology. Washington, D.C, Pan Américan Health Organization, 1992. p.1038-1043. (PAHO. Scientific Públication, 534).
Monografia em Inglês | LILACS | ID: lil-371022
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