Hand and finger, ultrasound-guided, percutaneous core needle biopsies: A safe procedure with high diagnostic accuracy.

Introduction/Purpose: To determine the diagnostic accuracy and complication rates of ultrasound-guided, percutaneous core needle biopsies of soft tissue masses in the hand and fingers. Methods: Reports from all ultrasound-guided procedures between 21 May 2014 and 17 March 2022 were queried for keywords including "hand", OR "finger", AND "biopsy". Patient demographics, lesion size and location, biopsy needle gauge and the number of cores obtained were recorded. The final pathology of the mass excision was then compared with the core needle biopsy (CNB) for each patient. Results: Sixty-six records were reviewed, and 37 patients met inclusion criteria. Maximum lesion diameter averaged 1.45 cm with a range between 0.4 and 4.3 cm. The frequency of needle gauges used was 14G (14%), 16G (24%), 18G (38%), 20G (11%) and 'not reported' (14%). The mean number of tissue cores obtained was 2.9 (SD 1.2; range 1 to 6), excluding nine cases that reported 'multiple'. The frequency of CNB diagnoses included tenosynovial giant cell tumour (TGCT) at 30%, ganglion cyst at 11% and epidermal inclusion cyst at 5%. CNB was 100% sensitive in detecting the three (8%) malignancies. Of the 37 tumours biopsied, 16 were surgically excised. One angiomyoma was originally diagnosed as a haemangioma on CNB, but all other histologic results were concordant for a diagnostic accuracy of 97%. Discussion: Small soft tissue masses in the hands and fingers, even those less than 1 cm, are often amenable to ultrasound-guided CNB. Performance under image guidance facilitates retrieval of core specimens adquate for histologic diagnosis with relatively few passes using higher gauge needles. Conclusion: Overall, ultrasound-guided CNB of the hand and fingers is safe and highly accurate in diagnosing soft tissue tumours. The accuracy is unrelated to the needle's gauge, the number of passes and the size of the lesions.

Unusual lipid poor spindle cell lipoma.

Spindle cell lipomas (SCLs) containing minimal fat are rare and can be diagnostically challenging due to their similar radiographic appearance to other benign and malignant tumours. SCLs are benign lipomatous tumours that typically occur in middle aged to elderly men as slow-growing, painless masses in the subcutaneous tissue of the posterior neck, shoulders or back. However, rarely these tumours can arise in unusual locations such as the lower extremities. We present an unusual case of a lipid poor SCL occurring in the lower extremity. Initial clinical and radiographic findings were suspicious for a malignancy. Two core biopsies demonstrated benign fibro collagenous tissue, so a marginal excision was performed. Final histopathological and immunohistochemical stains confirmed the diagnosis of an SCL. Radiologists, pathologists and oncologic surgeons should be aware of this lipomatous tumour's potential to present in unusual locations with minimal fatty components to increase confidence in radiologic-pathological concordance.

Soft Tissue Masses of the Hand: A Review of Clinical Presentation and Imaging Features.

More than 15% of all soft-tissue tumors arise in the hand. Because of the location of these tumors, even small abnormalities may be alarming to patients on presentation. Although the majority of lesions are benign and can be diagnosed solely by history and physical examination, additional imaging workup may be required to confirm a diagnosis or define anatomic extent of involvement. This paper aims to review the basic epidemiology, clinical presentation, imaging findings, and treatment options of the more common soft-tissue tumors of the hand.

Musculoskeletal MRI of Nontraumatic Emergencies.

A wide range of nontraumatic musculoskeletal conditions may require emergent or urgent management to avoid adverse clinical outcomes. These entities include bone and soft tissue infections, tissue necrosis, impending pathologic fracture or fungating tumor, and pseudoaneurysms. In this review, the magnetic resonance imaging appearance of these various entities is presented and discussed with the aim of improving radiologist and clinician recognition of the importance of key imaging findings in each case.

Diagnostic accuracy of preoperative magnetic resonance imaging for detecting subscapularis tendon tears: a diagnostic test study.

BACKGROUND: The accuracy of magnetic resonance imaging (MRI) for making the diagnosis of subscapularis tears presents wide variation in the literature and there are few prospective studies. OBJECTIVE: To compare the findings from MRI and arthroscopy for diagnosing subscapularis tears. DESIGN AND SETTING: Diagnostic test study performed in a tertiary care hospital. METHODS: We included patients who underwent arthroscopic rotator cuff repair and who had firstly undergone high magnetic field MRI without contrast. The images were independently evaluated by a shoulder surgeon and two musculoskeletal radiologists. Sensitivity, specificity, positive and negative predictive values, accuracy and inter and intra-observer agreement were calculated. RESULTS: MRIs on 200 shoulders were evaluated. The incidence of subscapularis tears was 69.5% (41.5% partial and 28.0% full-thickness). The inter and intra-observer agreement was moderate for detection of subscapularis tears. The shoulder surgeon presented sensitivity of 51.1% to 59.0% and specificity of 91.7% to 94.4%. The radiologists showed sensitivity of 83.5% to 87.1% and specificity of 41% to 45.9%. Accuracy ranged from 60.5% to 73.0%. CONCLUSION: The 1.5-T MRIs without contrast showed mean sensitivity of 70.2% and mean specificity of 61.9% for detection of subscapularis tears. Sensitivity was higher for the musculoskeletal radiologists, while specificity was higher for the shoulder surgeon. The mean accuracy was 67.6%, i.e. lower than that of rotator cuff tears overall.

Evaluation of ulnar variance on wrist MR imaging: is it a reliable measure?

OBJECTIVE: To determine if ulnar variance can be evaluated by magnetic resonance (MR) imaging and if this measure can be used as a reliable indicator when correlated to the gold standard technique, conventional radiography (CR). MATERIALS AND METHODS: From January to July 2018, the MR images of 64 participants, comprising 66 wrists (mean age 34.9 years; 33 females; 31 males), were obtained. Among those, 29 were referred for evaluation of the wrist for different medical reasons and 35 were asymptomatic volunteers from our radiology group. All subjects had a plain radiography of the wrist in a posteroanterior view with a mean interval between images of 1 day. Local ethics committee approved the study and written informed consent was obtained from all patients. Two musculoskeletal radiologists evaluated the images. Correlation coefficients and a linear regression model were used for statistical analyses. RESULTS: Intra- and inter-observer analyses were performed for both diagnostic methods with results showing concordance (intra-observer: kappa score: MR 0.915/CR 0.931; p < 0.05; inter-observer: kappa score: MR 0.857/CR 0.931; p < 0.05). The intraclass correlations of MR and CR to evaluate agreement between the radiologists was slightly higher for radiologist #1 (0.771) than for radiologist #2 (0.659). A linear regression model showed good model fit indicating that MR does correlate with the ulnar variance as measured by CR (CR = 0.554 + 0.897 × MR, R2 = 0.665). CONCLUSION: Although CR is the gold standard method for the evaluation of ulnar variance, our study demonstrated that MR can be used as a reliable qualitative option.

Magnetic Resonance Imaging Evaluation of the Anterolateral Ligament in Acute Anterior Cruciate Ligament Injuries in an Adolescent Population.

PURPOSE: To evaluate the frequency of anterolateral ligament (ALL) injuries in acute anterior cruciate ligament (ACL) injuries in adolescent patients using magnetic resonance imaging (MRI) and characterize other potential intra- and extra-articular knee injuries that are associated with ALL injuries. METHODS: Patients between 14 and 17 years of age with acute ACL injuries (trauma for <3 weeks before examination) were retrospectively evaluated with MRI over 24 months (January 2016-December 2017). Among this population, ALL was classified as not visible, normal, or injured. Injuries were separated into strains (partial injuries), complete injuries, or Segond fractures. Possible abnormalities of the menisci, collateral ligaments, popliteal tendon, posterior cruciate ligament (PCL), iliotibial tract (ITT), and bone injuries were evaluated. Associations were calculated between ALL injuries and injuries of these other knee structures, as well as age and gender. RESULTS: ALL was visible in 171 of the 184 MRI-evaluated knees (92.9%). ALL was considered normal in 68 (39.8%) and damaged in 103 (60.2%) patients. ALL injuries were considered partial in 56 (54.4%) and total in 44 (42.7%) cases. Only 3 (2.9%) cases were Segond fractures. ALL injuries were associated with ITT (P < .0001), lateral meniscus (P = .04), lateral collateral ligament (P = .01), popliteal tendon (P = .001), and medial collateral ligament (P = .009) injuries, in addition to bone contusions in the lateral compartment of the knee (P < .0001). There was no correlation between ALL injuries and medial meniscus (P = .054) or PCL (P = .16) injuries. CONCLUSIONS: MRI evaluation showed ALL injuries are present in 60.2% of acute ACL injuries in adolescent patients. These injuries are associated with the medial and lateral collateral ligaments, ITT, lateral meniscus injuries, and bone contusions, but they are not associated with medial meniscus or PCL injuries. LEVEL OF EVIDENCE: Level IV, case series.

Effect of muscle contractions on cartilage: morphological and functional magnetic resonance imaging evaluation of the knee after spinal cord injury.

OBJECTIVE: To evaluate the effect of complete absence of muscle contractions on normal human cartilage in the presence of joint motion. METHODS: Patients with complete acute spinal cord injuries were enrolled. All patients underwent magnetic resonance imaging (MRI) on both knees as soon as their medical condition was stable and at six months after the primary lesion. All patients received rehabilitation treatment that included lower-limb passive motion exercises twice a day. The MRIs were analyzed by two radiologists with expertise in musculoskeletal disorders. A region of interest was established at the patellar facets and trochlea, and T2 relaxation times were calculated. The area under the cartilage T2 relaxation time curve was calculated and standardized. RESULTS: Fourteen patients with complete spinal cord injuries were enrolled, but only eight patients agreed to participate in the study and signed the informed consent statement. Two patients could not undergo knee MRI due to their clinical conditions. Initial knee MRIs were performed on six patients. After six months, only two patients underwent the second bilateral knee MRI. Both patients were neurologically classified as Frankel A. An increase in T2 values on the six-month MRI was observed for both knees, especially in the patellofemoral joint. CONCLUSION: The absence of muscle contractions seems to be deleterious to normal human knee cartilage even in the presence of a normal range of motion. Further studies with a larger number of patients, despite their high logistical complexity, must be performed to confirm this hypothesis.

OBJETIVO: Avaliar o efeito da completa ausência de contração muscular na cartilagem humana normal na presença de movimento articular. MÉTODOS: Pacientes com lesão completa da medula espinal foram incluídos. Todos os pacientes foram submetidos à ressonância magnética (RM) em ambos os joelhos assim que as condições clínicas foram estabilizadas e depois de seis meses da lesão inicial. Todos os pacientes receberam tratamento de reabilitação que incluía movimentos passivos para exercitar os membros inferiores duas vezes por dia. RM foram analisadas por dois radiologistas com experiência em doenças musculoesqueléticas. As regiões de interesse consideradas foram as da patela e na tróclea, e os tempos de relaxamento T2 foram calculados. A área da cartilagem abaixo dos valores de relaxamento em T2 foi calculada e padronizada. RESULTADOS: Catorze pacientes com lesão medular completa foram incluídos, porém apenas oito pacientes concordaram em participar do estudo e assinaram o termo de consentimento informado. Dois pacientes não puderam fazer RM dos joelhos devido às condições clínicas. RM inicial foi feita em seis pacientes. Após seis meses, apenas dois pacientes fizeram a segunda RM de ambos os joelhos. Ambos estavam em condição neurológica classificada como Frankel A. Um aumento dos valores em T2 no sexto mês foi observado em ambos os joelhos, especialmente na articulação patelofemoral. CONCLUSÃO: A ausência de contração muscular parece ser deletéria à cartilagem do joelho humano normal, mesmo na presença de movimentos articulares normais. Mais estudos com um número maior de pacientes devem ser feitos para confirmar esta hipótese.

Effect of muscle contractions on cartilage: morphological and functional magnetic resonance imaging evaluation of the knee after spinal cord injury / Efeito da contração muscular na cartilagem: avaliação morfológica e funcional por imagens de ressonância magnética do joelho após trauma medular

ABSTRACT OBJECTIVE: To evaluate the effect of complete absence of muscle contractions on normal human cartilage in the presence of joint motion. METHODS: Patients with complete acute spinal cord injuries were enrolled. All patients underwent magnetic resonance imaging (MRI) on both knees as soon as their medical condition was stable and at six months after the primary lesion. All patients received rehabilitation treatment that included lower-limb passive motion exercises twice a day. The MRIs were analyzed by two radiologists with expertise in musculoskeletal disorders. A region of interest was established at the patellar facets and trochlea, and T2 relaxation times were calculated. The area under the cartilage T2 relaxation time curve was calculated and standardized. RESULTS: Fourteen patients with complete spinal cord injuries were enrolled, but only eight patients agreed to participate in the study and signed the informed consent statement. Two patients could not undergo knee MRI due to their clinical conditions. Initial knee MRIs were performed on six patients. After six months, only two patients underwent the second bilateral knee MRI. Both patients were neurologically classified as Frankel A. An increase in T2 values on the six-month MRI was observed for both knees, especially in the patellofemoral joint. CONCLUSION: The absence of muscle contractions seems to be deleterious to normal human knee cartilage even in the presence of a normal range of motion. Further studies with a larger number of patients, despite their high logistical complexity, must be performed to confirm this hypothesis.

RESUMO OBJETIVO: Avaliar o efeito da completa ausência de contração muscular na cartilagem humana normal na presença de movimento articular. MÉTODOS: Pacientes com lesão completa da medula espinal foram incluídos. Todos os pacientes foram submetidos à ressonância magnética (RM) em ambos os joelhos assim que as condições clínicas foram estabilizadas e depois de seis meses da lesão inicial. Todos os pacientes receberam tratamento de reabilitação que incluía movimentos passivos para exercitar os membros inferiores duas vezes por dia. RMs foram analisadas por dois radiologistas com experiência em doenças musculoesqueléticas. As regiões de interesse consideradas foram as facetas da patela e a tróclea e os tempos de relaxamento T2 foram calculados. A área da cartilagem abaixo dos valores de relaxamento em T2 foi calculada e padronizada. RESULTADOS: Foram incluídos 14 pacientes com lesão medular completa, porém apenas oito concordaram em participar do estudo e assinaram o termo de consentimento informado. Dois pacientes não puderam fazer RM dos joelhos devido às condições clínicas. RM inicial foi feita em seis pacientes. Após seis meses, apenas dois pacientes fizeram a segunda RM de ambos os joelhos. Ambos estavam em condição neurológica classificada como Frankel A. Um aumento dos valores em T2 no sexto mês foi observado em ambos os joelhos, especialmente na articulação patelofemoral. CONCLUSÃO: A ausência de contração muscular parece ser deletéria à cartilagem do joelho humano normal, mesmo na presença de movimentos articulares normais. Mais estudos com um número maior de pacientes devem ser feitos para confirmar essa hipótese.

Adesão ao tratamento farmacológico e controle dos níveis pressóricos de hipertensos acompanhados na Estratégia de Saúde da Família / Adherence to pharmacological treatment in hypertensive people followed in the Family Health Strategy

Introdução: A hipertensão arterial sistêmica é uma doença multifatorial com controle ainda difícil no Brasil, sendo a adesão ao tratamento um importante aspecto neste processo. Este estudo objetiva estimar a prevalência da adesão ao tratamento farmacológico anti-hipertensivo e sua associação com controle dos níveis pressóricos em indivíduos hipertensos acompanhados na Estratégia de Saúde da Família (ESF), em São Francisco do Conde, Bahia. Materiais e métodos: Trata-se de um estudo transversal, com 356 indivíduos hipertensos cadastrados no Programa de Acompanhamento de Hipertensos e Diabéticos (HIPERDIA). Osdados foram coletados através de visitas domiciliares, aplicação de questionário contendo o teste de Morisky-Green para avaliação da adesão farmacológica e realização da medida da pressão arterial. Resultados e discussão: Segundo o teste de Morisky-Green, 22,9% dos sujeitos foram considerados aderentes à terapia farmacológica, dado semelhante ao encontrado em outros estudos. O controle dos níveis pressóricos esteve associado com a adesão ao tratamento farmacológico. Os indivíduos aderentes à terapia farmacológica apresentaram maior média de idade e níveis pressóricos mais baixos. Conclusão: Nesse estudo a adesão ao tratamento farmacológico foi baixa entre os hipertensos, e esteve associada a melhores níveis pressóricos. Fazem-se necessárias diversas estratégias para melhor controle terapêutica desta doença

Introduction: Arterial systemic hypertension is a multifactorial disease hard to control in Brazil, and the adherence to treatment is a substantial aspect of this process. To estimate the prevalence of adherence to antihypertensive pharmacological treatment and its association with blood pressure level control in persons suffering from hypertension that were assisted by the Family Health Strategy (FHS), in São Francisco do Conde, Bahia, Brazil. Methods: It is a cross-sectional study, performed on 356 hypertense persons registered on the Hypertensive Diabetics Monitoring program (HIPERDIA). The data were collected through home visits, application of questionnaire containing the Morisky-Green test and two evaluations of blood pressure, both separated by at least 5 minutes within one another. Results: According to the Morisky-Green test, 22.6% of individuals did adhere to the pharmacological treatment, similar information were found in other studies. Blood pressure control was associated with medication adherence. Adherent individuals in this study possess higher average age and lower blood pressure levels. Conclusion: Medication adherence were low among hypertensive people and contributes to blood pressure level control. Various strategies are necessary for a better therapeutic control of this disease.

Melanoma metastático causando intussuscepção do intestino delgado: diagnóstico por 18F-FDG PET/TC / Metastatic melanoma causing small bowel intussusception: diagnosis by 18F-FDG PET/CT

Melanoma maligno é uma doença comum e agressiva que frequentemente causa metástase para o intestino delgado. Este estudo ilustra um caso de intussuscepção do intestino delgado causada por uma lesão metastática de melanoma visualizada à 18F-FDG PET/TC em uma paciente de 48 anos idade que realizou exame de reestadiamento.

Malignant melanoma is a common and aggressive disease that frequently causes metastases to the small bowel. This study illustrates a case of small bowel intussusception secondary to metastatic melanoma visualized at 18F-FDG PET/CT in a 48-year-old woman who had this examination for restaging purposes.