1.
Proc Natl Acad Sci U S A
; 67(4): 1824-6, 1970 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5275379
RESUMO
Experimental details are reported for a previously described synthesis of cecropia juvenile hormone.
Assuntos
Hormônios de Invertebrado/síntese química , Bombyx , Cromatografia Gasosa , Cromatografia em Camada Fina , Hormônios Juvenis/síntese química , Cetonas , Propilenoglicóis , Análise Espectral , Estereoisomerismo
2.
Proc Natl Acad Sci U S A
; 67(3): 1462-4, 1970 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5274469
RESUMO
A very short synthesis of the racemic cecropia hormone has been realized, utilizing a Claisen reaction. Methyl 6-hydroxy-3-methyl-7-methylene-2-trans-nonenoate, on treatment with the dimethyl ketal of 3-chloro-3-methyl-2-pentanone and a catalytic amount of 2,4-dinitrophenol, is transformed directly into methyl 11-chloro-3,11-dimethyl-7-ethyl-10-oxo-2-trans, 6-trans-tridecadienoate. Selective reduction gives a mixture of diastereoisomeric chlorohydrins separable by chromatography. The predominant threo-chlorohydrin is transformed into the juvenile hormone.
Assuntos
Hormônios de Invertebrado/síntese química , Métodos , Estereoisomerismo
3.
J Am Chem Soc
; 92(2): 425-7, 1970 Jan 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-5460980
