RESUMO
This publication is a continuation of our study for the treatment of pulmonary tuberculosis with early introduction of the intermittent methods. Early results were presented in a preliminary reports (Pneumonol. Alergol. Pol., 1995, 63, 57). From among 33 patients who were treated in this way, two-year follow-up was performed in 29 persons (we lost contact with two persons, 1 patient died from other reasons, and the next one was excluded for ambulatory prolongation of II phase of the treatment). 15 patients were supervised directly in our Department, and the others were estimated from records of Regional Antituberculosis Outpatient Clinics. Two years after the completion of therapy all 29 patients remained smear-negative and radiologically stable. On this basis, we assumed that results of the treatment of smear-positive pulmonary tuberculosis with early introduction of the intermittent methods are as good as standard therapy.
Assuntos
Antituberculosos/administração & dosagem , Tuberculose Pulmonar/tratamento farmacológico , Adulto , Idoso , Idoso de 80 Anos ou mais , Esquema de Medicação , Feminino , Seguimentos , Humanos , Pulmão/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Radiografia , Resultado do Tratamento , Tuberculose Pulmonar/diagnósticoRESUMO
We described the case of otitis media tuberculosa at the patient suffered from lung tuberculosis. Because of rare appearance and nonspecific running OMT is difficult to diagnose and correct treatment. At the described case fast and exact diagnosis maid possible, successfully ended, treatment.
Assuntos
Otite Média/complicações , Tuberculose Pulmonar/complicações , Tuberculose/diagnóstico , Adulto , Humanos , Masculino , Tuberculose/complicações , Tuberculose Pulmonar/diagnósticoRESUMO
The results of the treatment 33 patients for smear-positive pulmonary tuberculosis with Isoniazid, Rifampicin, Pyrazinamide and Streptomycin administrated during first two weeks daily, from 3 to 8 week also with these four drugs but in a little higher doses twice weekly and next Isoniazid and Rifampicin during 9-26 weeks also twice weekly as in standard Polish model were described. After therapy with above described regimen all patients became smear-negative and radiological improvement was observed. Drugs in higher doses were well tolerated. Only abnormality in laboratory findings was temporary elevated level of uric acid, which recovered to normal values before the end of therapy. Costs of antituberculous drugs were used in this regimen is approximately 35% lower than standard model in Poland.
Assuntos
Antituberculosos/administração & dosagem , Tuberculose Pulmonar/tratamento farmacológico , Adulto , Idoso , Idoso de 80 Anos ou mais , Esquema de Medicação , Quimioterapia Combinada , Feminino , Humanos , Isoniazida/administração & dosagem , Masculino , Pessoa de Meia-Idade , Pirazinamida/administração & dosagem , Rifampina/administração & dosagem , Estreptomicina/administração & dosagem , Tuberculose Pulmonar/metabolismo , Tuberculose Pulmonar/patologia , Ácido Úrico/metabolismoRESUMO
On the basis of two reported clinical cases, patient K. K. in whom preliminary diagnosis of tumour of the left pulmonary hilus was the result of valvular heart disease, and patient A. L. in whom similar symptoms, signs and radiological manifestations developed in the course of bronchogenous microcellular lung cancer, it was demonstrated that both the similar radiological picture and similar symptoms in the patients could be caused by totally different nosological entities. Effective differential diagnosis is of decisive importance especially for those patients in whom preliminary diagnosis of the pulmonary hilus turns out to have neoplastic basis. Such diagnosis can be made only in a well-equipped specialistic department.