RESUMO
INTRODUCTION: Achondroplasia is a genetic disorder known for short stature and skeletal abnormalities. CASE REPORT: We present a case of narrowing of the foramen magnum from a large opisthion extending to the spinal canal. CONCLUSION: Foramen magnum stenosis and cervicomedullary stenosis are potentially life threatening neurological manifestations of achondroplasia.
Assuntos
Acondroplasia , Compressão da Medula Espinal , Humanos , Lactente , Constrição Patológica/etiologia , Constrição Patológica/cirurgia , Forame Magno/diagnóstico por imagem , Forame Magno/cirurgia , Acondroplasia/complicações , Compressão da Medula Espinal/diagnóstico por imagem , Compressão da Medula Espinal/etiologia , Compressão da Medula Espinal/cirurgiaRESUMO
We report all-electron and pseudopotential calculations of the ground-state energies of the neutral Ne atom and the Ne(+) ion using the variational and diffusion quantum Monte Carlo (DMC) methods. We investigate different levels of Slater-Jastrow trial wave function: (i) using Hartree-Fock orbitals, (ii) using orbitals optimized within a Monte Carlo procedure in the presence of a Jastrow factor, and (iii) including backflow correlations in the wave function. Small reductions in the total energy are obtained by optimizing the orbitals, while more significant reductions are obtained by incorporating backflow correlations. We study the finite-time-step and fixed-node biases in the DMC energy and show that there is a strong tendency for these errors to cancel when the first ionization potential (IP) is calculated. DMC gives highly accurate values for the IP of Ne at all the levels of trial wave function that we have considered.
Assuntos
Hospitais com Fins Lucrativos/economia , Internato e Residência/economia , Internato e Residência/tendências , Medicina Osteopática/tendências , Alocação de Custos , Educação de Pós-Graduação em Medicina/economia , Educação de Pós-Graduação em Medicina/tendências , Previsões , Humanos , Medicina Osteopática/economia , Medicina Osteopática/educação , Estados UnidosAssuntos
Artérias/análise , Coturnix , Glicosaminoglicanos/análise , Metenamina , Prata , Coloração e Rotulagem , Animais , Aorta/análise , Métodos , Microscopia EletrônicaRESUMO
Myofibrils from pig muscle inoculated and incubated with Pseudomonas fragi showed an extremely disrupted appearance as compared to uninoculated controls. There was an almost complete absence of material in the H zone, marked disruption of the A band (probably myosin), and some loss of dense material from the Z line. These changes indicated that marked proteolysis had occurred. Bacteria observed in spoiled muscle tissue exhibited protrusions or blebs on the outer surface of the cell walls. The blebs appeared to form detached globules that migrated into the muscle mass. Bacteria grown in non-muscle-containing media did not produce blebs, which indicates the blebs were induced by growth on muscle tissue. The possibility that the blebs and globules may contain a proteolytic enzyme responsible for myofibrillar disruption is discussed.
