[The pathomorphology of the intra- and extraorganic neural apparatus of the heart in congenital defects]. / Patomorfologiia intra- i ékstraorgannykh nervnykh priborov serdtsa pri vrozhdennykh ego porokakh.

Different components of the heart sympathetic and parasympathetic innervation were studied in 22 autopsy cases of congenital heart defects. Central efferent neurons in the lateral horns of the upper thoracic segments of the spinal cord and in the dorsal nucleus of the medulla oblongata are damaged stronger than the neurons of the upper neck and stellate sympathetic nodes and the heart intramural ganglia this resulting in the selective destruction of the preganglionic nervous conducting elements. It is suggested that the disturbance of the connection between the heart nervous structures and the central nervous system exerts a negative influence on its function.

[Pathology of microhemocirculatory vessels in congenital heart defects with left-to-right shunt]. / Patologiia sosudov mikrogemotsirkuliatsii pri vrozhdennykh porokakh serdtsa so sbrosom krovi sleva napravo.

Pathology of microcirculatory vessels of greater omentum and bulbar conjunctiva in children with congenital heart disease presenting with a left-to-right shunt was studied by biomicroscopic and morphologic methods. It has been shown that in this disorder of central hemodynamics the progressive reduction of true capillaries arises both in bulbar conjunctiva, and especially in the omentum. The authors believe that such deficit of tissue blood supply leads to reduction of density in terminal vascular networks and to the simplification of the construction of microcirculatory, in which the number of main microvessels (capillaries) increases, thus combining directly arterioles and venules, resulting in blood flow centralization and decrease of the efficiency of microcirculation.