Assuntos
Carcinoma/patologia , Linfonodos/patologia , Neoplasias da Glândula Tireoide/patologia , Adolescente , Carcinoma/epidemiologia , Carcinoma Papilar , Criança , Pré-Escolar , Feminino , Humanos , Metástase Linfática , Masculino , República de Belarus/epidemiologia , Câncer Papilífero da Tireoide , Neoplasias da Glândula Tireoide/epidemiologiaRESUMO
The clinico-morphological investigations of 117 children and adolescences with papillary thyroid carcinoma, surgically treated in the Republic Centre for Thyroid Tumors, Minsk, Belarus in 1995-2009 and dutifully followed-up have been studied. Ninety -five observations of all cases were sporadic, but 22 patients had been treated earlier from other neoplasm (Hodgkin's diseases, malignant lymphoma, leukemia, sarcoma, medulloblastoma). Epidemiologic, clinical and pathological peculiarities of thyroid carcinoma in Belarus were analyzed. A number of features distinguished "cryptogenic" and "iatrogenic" papillary thyroid carcinoma in children and adolescents were found out.
Assuntos
Carcinoma Papilar/patologia , Doença Iatrogênica , Segunda Neoplasia Primária/patologia , Neoplasias da Glândula Tireoide/patologia , Adolescente , Carcinoma Papilar/etiologia , Carcinoma Papilar/cirurgia , Criança , Pré-Escolar , Feminino , Humanos , Masculino , Análise Multivariada , Invasividade Neoplásica , Metástase Neoplásica , Segunda Neoplasia Primária/etiologia , Segunda Neoplasia Primária/cirurgia , Neoplasias da Glândula Tireoide/etiologia , Neoplasias da Glândula Tireoide/cirurgiaRESUMO
Untoward side-effects of chemoradiotherapy were compared in 48 children treated for brain tumors and those in remission lasting from less than 12 months to 11 years. The investigation concerned disturbances in the neurologic, endocrine, cardiovascular, urinary, hepatobiliary and psychic systems; neurologic ones proved the most frequent. No cases of heart failure were reported among patients with brain tumors during remission. Hormonal study revealed inhibited thyroid function in brain tumor sufferers.
