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J Comb Chem ; 12(1): 181-5, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-19921823

RESUMO

A simple and efficient microwave assisted synthesis of imidazobenzoxazines, imidazobenzoxazin-5-ones, and imidazobenzoxazin-5-thiones with broad chemistry scope is described. The molecules were prepared both under conventional as well as microwave heating conditions, to provide in high yields with clean and scalable reactions a small library of imidazole-based privileged structures for drug discovery.


Assuntos
Técnicas de Química Combinatória/métodos , Imidazóis/síntese química , Micro-Ondas , Estrutura Molecular
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