RESUMO
Cleft lip with or without cleft palate [CL(P)] has a high prevalence [corrected] in the northern Netherlands. Several epidemiological parameters for oral clefts, including both CL(P) and cleft palate (CP), were analysed and compared with the literature. Except for the high prevalence at birth of isolated CL(P) no major differences in the pattern of occurrence described elsewhere were found. So far, descriptive epidemiological studies have not given any insight into the aetiology of this high CL(P) prevalence [corrected] in the Northern Netherlands. Therefore, case control studies on possible risk factors have been initiated.
Assuntos
Fenda Labial/epidemiologia , Fissura Palatina/epidemiologia , Aborto Induzido/estatística & dados numéricos , Adulto , Feminino , Morte Fetal/epidemiologia , Humanos , Incidência , Recém-Nascido , Masculino , Idade Materna , Pessoa de Meia-Idade , Países Baixos/epidemiologia , Sistema de RegistrosRESUMO
For birth years 1981-1986, 1251 children/foetuses with congenital anomalies were reported to the regional EUROCAT registration of the northern Netherlands (2.5% of all live and stillbirths). In this article the total birth prevalence for over 30 individual congenital anomalies is presented for the first time in the Netherlands. The prevalence registered for neural tube defects is higher than in EUROCAT-centres elsewhere in continental Europe. The prevalence of cleft lip with or without cleft palate is, as in Denmark, higher than in other EUROCAT-centres.
