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1.
JAMA Ophthalmol ; 141(12): e232948, 2023 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-38127083

RESUMO

This case report describes a diagnosis of Curvularia fungal keratitis in a man aged 60 years who presented with a paracentral corneal infiltrate in the right eye with tentacular projections.


Assuntos
Úlcera da Córnea , Ceratite , Pythium , Humanos , Úlcera da Córnea/diagnóstico , Úlcera da Córnea/tratamento farmacológico , Ceratite/diagnóstico , Ceratite/tratamento farmacológico , Ceratite/microbiologia
2.
Eur J Ophthalmol ; 31(6): NP1-NP4, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32493136

RESUMO

A 50-year-old female patient presented with protrusion of the left eye for 1 month. Examination showed abaxial proptosis, restriction of extraocular movements, and elevated intraocular pressure. Computed tomography of the orbits showed soft tissue enhancing lesion in the superolateral aspect of the left orbit with lytic lesions in calvarium. Fine needle aspiration cytology of the lesion revealed a diagnosis of plasmacytoma with positive CD138 and CD38 immunohistochemical stains. Erythrocyte sedimentation rate, C-reactive protein and serum lactate dehydrogenase were elevated. Serum protein electrophoresis revealed hypergammaglobulinemia, and bone marrow biopsy revealed 6% plasma cells. The patient was started on chemotherapy with bortezomib, dexamethasone and lenalidomide by the medical oncologist. Significant improvement in proptosis and extraocular movements noted on follow-up. Orbital myeloma may be the first manifestation of systemic disease.


Assuntos
Exoftalmia , Mieloma Múltiplo , Neoplasias Orbitárias , Plasmocitoma , Biópsia por Agulha Fina , Exoftalmia/diagnóstico , Exoftalmia/tratamento farmacológico , Exoftalmia/etiologia , Feminino , Humanos , Pessoa de Meia-Idade , Mieloma Múltiplo/diagnóstico , Mieloma Múltiplo/tratamento farmacológico , Neoplasias Orbitárias/diagnóstico , Neoplasias Orbitárias/tratamento farmacológico , Plasmocitoma/diagnóstico , Plasmocitoma/tratamento farmacológico , Tomografia Computadorizada por Raios X
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