[Genital infections in girls with type 1 diabetes]. / Genitalni infektsii pri momicheta s tip 1 diabet.

The aim of the study was to investigate the relation between genital infections (frequency, etiology, clinical presentation) among girls with type 1 diabetes and some factors as age of the girls, duration and metabolic control of diabetes. Forty-three girls with type 1 diabetes and twelve healthy girls for controls were involved in the study. Methods used are: genital tract inspection, direct microscopy and cultures from genital discharge and urine. Glycaemic control in the diabetic girls was assessed by measuring total glycosylated haemoglobin. The results show vulvovaginal candidiasis in 27 (62.8%) in diabetic girls versus 2 (16.6%) in controls (p < 0.01). There was clear prevalence of non-albicans Candida species. Concomitant infection with bacterial pathogens were proved in only 6 (13.9%) of diabetic girls and 1 (8.5%) of the controls. The clinical presentation of genital candidiasis was vulvovaginitis and most of the affected diabetic girls (88.9%) were in puberty period. There was no relation between duration and metabolic control of diabetes and genital infections.

[Nosocomial enterobacter - sepsis in neonatal intensive care unit in Pleven]. / Nozokomialen enterobacter - sepsis v neonatalogichno intenzivno otdelenie - Pleven.

At the recent years considerably increased the role of Enterobacter spp as causes of nosocomial sepsis in different intensive units. It is determined of their possibilities to change quick antibiotic resistance especially to third generation cephalosporins and wide insemination of the environment. During the period from 29.10.1997 to 30.12.1997 in Neonatal intensive care unit--Pleven have been registered 9 cases of nosocomial sepsis caused by Enterobacter aerogenes. The clinic picture run with shock, temperature instability, hyperbilirubinemia, mottling respiratory insufficiency, I/T ratio > 0.2. Thrombocytopenia. Detection of the pathogen organisms present wide antibiotics resistance to cephalosporins. The microbiological control of the environment have been isolated Enterobacter spp from neonatal intensive unit, delivery room, unit for healthy newborn. The persistence of Enterobacter infections is a result of low supply of household linen, detergents, single-used products and widely used of cephalosporins, insufficient staff and overpopulation with patients.

[A clinical and microbiological study of bacterial vaginosis and vaginitis in pregnant women]. / Kliniko-mikrobiologichno prouchvane na bakterialnite vaginozi i vaginiti pri bremenni zheni.

Infectious complications in pregnancy and delivery are still y serious problem in obstetrical, gynecological and neonatological practice. The main part of them are caused from the anaerobic organisms associated with bacterial vaginosis as well from sexually transmitted pathogens. In this study we present data about the frequency of spreading of bacterial vaginosis and vaginitis in pregnant women at different stages of pregnancy. We held y study of 106 pregnant women aged between 15 and 35, registrated at the Pregnancy Consultation Office in eleven. About half of the women did not have data for genital discharge and the microbiological analysis showed normal vaginal flora. Two thirds of the rest investigated women had data for candidiasis, bacterial vaginosis, or both. Only one case of Trichomonas vaginalis-vaginitis was detected. The results from the microscopic examination of the specimens from 10 (9.4%) of the women were suspected for N. gonorrhoeae and/or Chlamydia trachomatis-cervicitis. Group B streptococci in significant quantity was found in five cases. These results showed high frequency of spreading of bacterial vaginosis and cervico-vaginitis in pregnant women.