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1.
Acta Crystallogr Sect E Struct Rep Online ; 70(Pt 10): o1094-5, 2014 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-25484690

RESUMO

The title Schiff base compound, C25H20N2, crystallizes with two independent mol-ecules (A and B) in the asymmetric unit. In both mol-ecules, the imine group is approximately coplanar with the pyridine ring, with N-C-C-N torsion angles of 170.1 (3) and -172.0 (3) Å. In the crystal, A and B dimers are linked by pairs of C-H⋯π inter-actions and further C-H⋯π bonds link the dimers into a three-dimensional network.

2.
Southeast Asian J Trop Med Public Health ; 36(6): 1543-51, 2005 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-16610660

RESUMO

The antimutagenic activity of Sesbania javanica Miq. or Sano, an edible vegetable flower DMSO extract against aflatoxin B1 (AFB1) benzo (a) pyrene [B(a)P], was evaluated by means of the Ames' test. The Sesbania javanica Miq. flower DMSO extract showed a strong inhibitory effect against AFB1 and B(a)P mutagens. A search to isolate the major flavonoid in Sesbania javanica Miq. flower extract found the flavonol glycoside, Quercetin 3-2(G)-rhamnosylrutinoside, which was confirmed by its physicochemical properties as a major constituent of the flower. Quercetin 3-2(G)-rhamnosylrutinoside (207 microg/plate) also showeda strong inhibitory effect against AFB1 and B(a)P with a more than 70% inhibition rate.


Assuntos
Aflatoxina B1 , Antimutagênicos/farmacologia , Flavonoides/farmacologia , Flores , Glicosídeos/farmacologia , Extratos Vegetais/farmacologia , Sesbania , Dimetil Sulfóxido , Humanos , Testes de Mutagenicidade
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