Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
J Clin Immunol ; 42(3): 441-447, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-34978002

RESUMO

RATIONALE: Transient myopericarditis has been recognised as an uncommon and usually mild adverse event predominantly linked to mRNA-based COVID-19 vaccines. These have mostly occurred in young males after the second dose of mRNA COVID-19 vaccines. OBJECTIVES: Fulminant necrotising eosinophilic myocarditis triggered by a variety of drugs or vaccines is an extremely rare hypersensitivity reaction carrying a substantial mortality risk. Early recognition of this medical emergency may facilitate urgent hospital admission for investigation and treatment. Timely intervention can lead to complete cardiac recovery, but the non-specific clinical features and rarity make early diagnosis challenging. FINDINGS: The clinical and pathological observations from a case of fatal fulminant necrotising myocarditis in a 57-year-old woman, following the first dose of the Pfizer-BioNTech vaccine, are described. Other causes have been discounted with reasonable certainty. CONCLUSION: These extremely rare vaccine-related adverse events are much less common than the risk of myocarditis and other lethal complications from COVID-19 infection. The benefits of vaccination far exceed the risks of COVID-19 infection.


Assuntos
COVID-19 , Hipersensibilidade , Transtornos Leucocíticos , Miocardite , Vacinas , Vacina BNT162 , COVID-19/diagnóstico , Vacinas contra COVID-19/efeitos adversos , Feminino , Humanos , Hipersensibilidade/complicações , Masculino , Pessoa de Meia-Idade , Miocardite/diagnóstico , Miocardite/etiologia , RNA Mensageiro
2.
Am J Forensic Med Pathol ; 24(2): 193-7, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12773861

RESUMO

Throughout the last century, there has been a marked decline in obstetric maternal deaths, resulting in an increase in the proportion of nonobstetric deaths among pregnant women. Trauma, in particular, has become a leading cause of maternal death. We report the case of a 20-year-old primigravid woman who was involved in a motor vehicle crash at 36 weeks gestation. The woman developed abruptio placentae, followed by disseminated intravascular coagulation, adult respiratory distress syndrome, and shock, and died the day after the crash. Widespread pulmonary embolization by chorionic villi was identified at autopsy. This report discusses traumatic maternal deaths, with emphasis on the differences in injury pattern observed in pregnant trauma victims in comparison with other adults. It is important that the pathologist be aware of these problems so that an accurate cause of death can be identified in cases of maternal death after trauma. Also discussed is the relationship between trauma and placental abruption and the mechanism of death in the patient. To the authors' knowledge, this is the first reported case of extensive embolism of chorionic villi to the lungs after trauma.


Assuntos
Acidentes de Trânsito , Vilosidades Coriônicas/patologia , Complicações Hematológicas na Gravidez/patologia , Embolia Pulmonar/patologia , Descolamento Prematuro da Placenta/complicações , Adulto , Coagulação Intravascular Disseminada/complicações , Coagulação Intravascular Disseminada/diagnóstico , Evolução Fatal , Feminino , Morte Fetal/etiologia , Parada Cardíaca/complicações , Parada Cardíaca/terapia , Humanos , Gravidez , Embolia Pulmonar/complicações
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...