1.
2.
J Am Chem Soc
; 123(19): 4641-2, 2001 May 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11457267
3.
Org Lett
; 2(10): 1423-6, 2000 May 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-10814463
RESUMO
[equation--see text] A catalytic system for the mild amination of aryl chlorides is described. This system consists of a Pd(0) precursor and a dihydroimidazoline carbene ligand, which is generated in situ from its protonated tetrafluoroborate salt (2). Using this catalyst, aryl and heteroaryl chlorides react with secondary amines and anilines within hours at room temperature. Turnover numbers as high as 5000 are obtained at elevated temperatures for reaction of morpholine with an unactivated aryl chloride.