1.
Rheumatology
; 6: 361-7, 1975.
Artigo
em Inglês
| MEDLINE
| ID: mdl-1202607
RESUMO
Ten day embryonated eggs have been used for testing supernatants of pooled RA synovial tissues for the presence of the RA-active agent. A high thermal resistance of the agent was observed up to 40 min of heating both at 100 and 121 degrees C with complete loss of infectivity only after 60 min at 121 degrees C. The high thermal resistance at 121 degrees C suggested that the active agent does not depend on a double-stranded DNA or RNA. It probably has no protein component and has a minimal number of subunits for replication. The CsC1 ultracentrifugation identified a concentration of high infectivity at densities in the range of 1.440-1.490 g/ml in five experiments.
Assuntos
Artrite Reumatoide/microbiologia , Temperatura Alta , Animais , Artrite Reumatoide/transmissão , Centrifugação Isopícnica , Embrião de Galinha , Galinhas
2.
Oncology
; 29(4): 294-301, 1974.
Artigo
em Inglês
| MEDLINE
| ID: mdl-4842403