RESUMO
Serum IgE, GM-CSF and IL-4 concentrations were measured in 35 children (3 to 18 years of age) with bronchial asthma in I and II clinical stage. Control group consisted of 10 healthy children (6 to 9 years of age) without any symptoms of inflammatory process. All measurements were performed by ELISA tests. The concentration of serum IL-4 was statistically significantly higher in children with bronchial asthma (0.06 ng/ml) than in the control group (0.01 ng/ml). Serum concentration of GM-CSF was lower in children with bronchial asthma than in control group (4.4 and 8.44 pg/ml respectively).
Assuntos
Asma/sangue , Fator Estimulador de Colônias de Granulócitos e Macrófagos/sangue , Imunoglobulina E/sangue , Interleucina-4/sangue , Adolescente , Asma/patologia , Criança , Pré-Escolar , Ensaio de Imunoadsorção Enzimática , Feminino , Humanos , MasculinoRESUMO
The authors used in children in with recurrent respiratory infections in 28 cases isoprenosine, in 30 climatic therapy and in 15 isoprenosine followed by climatic therapy. Isoprenosine was used in a dose 50 mg per kg b.w. for two weeks, followed by 10 days of an interruption, after which isoprenosine was gain given for ten days. Climatic therapy was carried out for six weeks. Thirty healthy children of the same age made up the control. Good or excellent results were seen in 19 out of 28 children treated with isoprenosine, in 16 out of 30 that underwent climatic therapy, and 11 out of 15 in which both modes were used. The authors discuss their own experience in treating children with recurrent respiratory infections suggesting that this model for treating sick cases be used, observing good results in two thirds.