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1.
Cureus ; 15(6): e41222, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37525762

RESUMO

Intracholecystic papillary neoplasm (ICPN) is a grossly visible, mass-forming, noninvasive epithelial neoplasm arising from the mucosa and projecting into the lumen of the gallbladder. ICPN is a lesser-known tumor of the gallbladder lining, which although has a better prognosis compared to gallbladder adenocarcinoma carries the potential for metastatic transformation with spread to other organs. ICPN is found incidentally on imaging or during postop histological evaluation. However, we present a unique case of ICPN that was incidentally diagnosed in a 72-year-old Eastern European woman following cholecystectomy for acute cholecystitis and was missed on preoperative imaging. Follow-up protocols of ICPN are poorly understood and vastly underreported. We discuss this patient's findings in light of current literary evidence available on ICPN and outline future directions for better clinical understanding. We also highlight the need for screening guidelines in light of known risk factors to better understand the natural history of the disease to prevent malignant transformation into invasive gallbladder carcinoma.

2.
Cureus ; 15(6): e40523, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37461784

RESUMO

Gallstones are the primary cause of symptomatic gallbladder disease and lead to a significant portion of hospitalizations related to gastrointestinal diseases. The gold standard treatment for gallbladder disease continues to be cholecystectomy, which is commonly done laparoscopically, and improves patients' quality of life. With any surgical intervention there are inherent risks, and in the setting of severe illness, the risk of potential complications increases immensely. Postoperative altered mental status, namely, delirium, may occur in the elderly and a high index of suspicion is required to recognize the clinical signs for swift diagnosis and management. This case involves a 61-year-old male who underwent laparoscopic cholecystectomy and developed persistent delirium during the hospital course. This report aims to explore the multiple risk factors that lead to postoperative delirium and review the diagnostic and therapeutic strategies utilized in managing this patient.

3.
Cureus ; 15(5): e38393, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37265923

RESUMO

We report the case of a 56-year-old male presenting with nine days of constipation and absence of flatus without any improvement and who had received conservative management after recent admission at an external hospital. Upon further investigation, the patient was diagnosed with rectosigmoid adenocarcinoma and was successfully surgically treated without any perioperative complications. This case highlights the importance of early detection and interventions necessary to prevent progression of colorectal adenocarcinoma. Easily manageable symptoms such as constipation may require further evaluation by implementing a constipation scoring system to avoid missed diagnoses such as cancer and metastasis. Therefore, the association between constipation and colorectal carcinoma warrants further research investigations as well as clinician awareness to prevent life-threatening complications.

4.
Cureus ; 15(4): e37511, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37187641

RESUMO

Diverticulitis is a significant contributor to the number of hospital admissions and healthcare costs in Western societies. The authors present the case of an otherwise healthy 33-year-old Hispanic male presenting to the emergency department with complaints of abdominal pain, pneumaturia, and hematochezia. The patient had no underlying risk factors, substantial prior medical history, or typical symptoms of diverticulitis. He was diagnosed with acute diverticulitis with a presumed colovesical fistula. The unique clinical presentation and the intraoperative findings are discussed. The objective of this case report is to make clinicians aware of atypical presentations of acute diverticulitis and guide the appropriate diagnostic workup for young Hispanic males presenting to the emergency departments with complaints of abdominal pain.

5.
Ann Thorac Surg ; 102(2): e105-7, 2016 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-27449440

RESUMO

Endocarditis is a rare presentation for cytomegalovirus (CMV) infection. We present the case of a 49-year-old man who underwent mitral and tricuspid valve replacement for valvular CMV endocarditis. The patient's past medical history was significant for human immunodeficiency virus, intravenous drug abuse, and chronic hepatitis B. During his clinical course, he was found to have tricuspid and mitral valve vegetations. After progressive valvular destruction despite antibiotic therapy, he underwent successful mitral and tricuspid valve replacement. Pathologic analysis of the culture-negative valve specimens were found to contain inclusion bodies consistent with CMV, and quantitative serum polymerase chain reaction returned a highly elevated CMV DNA count.


Assuntos
Infecções por Citomegalovirus/diagnóstico , Endocardite/cirurgia , Endocardite/virologia , Implante de Prótese de Valva Cardíaca/métodos , Valva Mitral/cirurgia , Valva Tricúspide/cirurgia , Biópsia por Agulha , Infecções por Citomegalovirus/complicações , Ecocardiografia Transesofagiana/métodos , Endocardite/diagnóstico por imagem , Seguimentos , Doenças das Valvas Cardíacas/diagnóstico por imagem , Doenças das Valvas Cardíacas/cirurgia , Doenças das Valvas Cardíacas/virologia , Próteses Valvulares Cardíacas , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Valva Mitral/patologia , Valva Mitral/virologia , Medição de Risco , Resultado do Tratamento , Valva Tricúspide/patologia , Valva Tricúspide/virologia
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