[Aspects of morphology of photodynamic destruction]. / Nekotorye voprosy morfologii fotodinamicheskoi destruktsii.

The results of light and electron microscopic study of the photodynamic destruction of the mouse liver with the use of Russian and imported photosensitizers (PS) at the concentration peak are presented. Considerable differences in the primary targets are noted; the changes correlated at the tissue and ultrastructural level. The use of two PS showed the damage of the soluble part of the cytoplasm: generalized cytoplasm damage with the involvement of main cell organelles in one case and the destruction of the sinusoidal lining and the hepatocyte sinusoidal pole with a diffuse spread of changes beyond the main focus of the damage close to the vascular bed in the other. Theoretical importance and practical application of the study are discussed.

[Morphology of adrenergic and cholinergic innervation of the kidney as affected by spontaneous and ischemic renal hypertension in rats]. / Morfologiia adren- i kholinergicheskoi innervatsii pochki pri spontannoi i ishemicheskoi pochechnoi gipertensiiakh u krys.

The innervation of basic renal structures (vascular glomerular pole with juxtaglomerular apparatus and renal tubules) was experimentally studied in rats at different stages of spontaneous and Goldblatt hypertension. Both fluorescent determination of adrenergic innervation and histochemical identification of cholinergic innervation have shown that they increased in spontaneous and remained unchanged in renal hypertension. The data obtained confirm an important role of intrarenal innervation in the development of kidney "resettings" in spontaneous hypertension.

[Morphological evidence of celiac ganglion hyperfunction in spontaneous hypertension in rats]. / Morfologicheskie dokazatel'stva giperfunktsii chrevnogo gangliia pri spontannoi gipertenzii u krys.

To elucidate the role of the autonomous nervous system in formation of a specific renal "resetting", typical for arterial hypertension, in 8-week-old spontaneously hypertensive rats, a study was made of the morphology of the celiac ganglion as one of the main sources of renal innervation. Light and fluorescent microscopy demonstrate the hypertrophy of the neurons and their nuclei, an increase in the whole ganglion volume and the volume density of the SIF cells. This evidence for hyperactivity of the celiac ganglion attests to the involvement of the renal nervous system in the structural and functional reorganization ("resetting") at the early stages of hypertension as well as a manifestation of hyperactivity of the nervous system in this disease.