RESUMO
Biobanks produce and distribute biospecimens, ensuring their fitness for purpose and accurately qualifying them before distribution. In their efforts toward professionalization, biobanks can nowadays seek certification or accreditation. One of the requirements of these standards is regular participation in Proficiency Testing (PT) programs. An international PT program has been developed and provided to biobanks and other laboratories that perform specific tests to qualify different types of biospecimens. This PT program includes biospecimen testing schemes, as well as biospecimen processing interlaboratory exercises. This PT program supports the development of biobank quality assurance by providing the possibility to assess biobank laboratory performance and useful insights into biobank laboratory method performance characteristics and thus fulfill the demands from accreditation authorities.
Assuntos
Bancos de Espécimes Biológicos/organização & administração , Manejo de Espécimes/normas , Acreditação , Bancos de Espécimes Biológicos/normas , Humanos , Controle de QualidadeRESUMO
Liver transplantation is the therapeutic option of choice for acute and chronic end-stage liver disease. The indications and contraindications to liver transplantation have become established, as has the operative and postoperative management. This article provides a practical clinical approach to the evaluation and management of patients with acute and chronic liver failure, with particular emphasis on liver transplant recipient selection, clinical management, and complications. The goal is to provide helpful guidelines to caregivers involved in the multidisciplinary care of these complex patients.
