Core-Level Binding Energy Reveals Hydrogen Bonding Configurations of Water Adsorbed on TiO_{2}(110) Surface.

Using x-ray photoelectron spectroscopy of the oxygen 1s core level, the ratio between intact (D_{2}O) and dissociated (OD) water in the hydrated stoichiometric TiO_{2}(110) surface is determined at varying coverage and temperature. In the submonolayer regime, both the D_{2}O∶OD ratio and the core-level binding energy of D_{2}O (ΔBE) decrease with temperature. The observed variations in ΔBE are shown with density functional theory to be governed crucially and solely by the local hydrogen bonding environment, revealing a generally applicable classification and details about adsorption motifs.

Long-term non-invasive positive airway pressure ventilation in infants.

AIM: To evaluate the clinical application of long-term non-invasive ventilation (NIV) in infants with life-threatening ventilatory failure with regard to: diagnosis, age at initiation, indication for and duration of treatment, clinical outcome and mortality and adverse effects. PATIENTS AND METHODS: The medical records of 18 infants treated in a home setting during a 7-year period were reviewed. The criteria for ventilatory support were: (a) transcutaneous partial pressures of carbon dioxide (TcPCO(2)) >6.5 kPa and oxygen (TcPO(2)) < 8.5 kPa and (b) decreased cough ability and/or recurrent chest infections. RESULTS: The median age at initiation was 4 months (range 1-12). NIV was initiated because of hypoventilation in 12 infants and because of reduced cough ability and/or recurrent infections in six infants. Tracheotomy was eventually needed in two infants. The median duration of treatment was 24 months (range 1-84). NIV produced significant improvements, with median TcPCO(2) falling from 9.9 to 6.1 kPa, and median TcPO(2) rising from 9.8 to 11.1 kPa. CONCLUSION: NIV can be successfully and safely used in infants with prolonged life-threatening ventilatory failure, potentially avoiding intubation and tracheotomy.