[The fate of first cup arthroplasty implanted in slovakia.]. / Osud prvej implantovanej cup artroplastiky na Slovensku.

Authors describe a case of a patient, by whom the first cup arthroplasty in Slovakia was implanted by prof. Cervenanský in 1948. 17 years after the implantation a gradual onset of limitation in motion began. A painfull contracture developed with a functional shortening of the lower extremity. 50 years after the implantation of the cup arthroplasty a conversion to a cemented total hip prosthesis was successfuly realised with a good result. Key words: cup arthroplasty, prof. Cervenanský, conversion.

Human neoplastic cells in tissue culture: two established cell lines derived from giant cell tumor and fibrosarcoma.

The establishment and cultivation of two human neoplastic cell lines is described. The cell line B-5GT was derived from bone giant cell tumor and B-6FS from poorly differentiated fibrosarcoma. In comparison to the normal skin fibroblasts both cell lines have a potential for "indefinite" multiplication in vitro and they exhibit growth properties which are associated with malignant transformation. The parameters investigated included cell morphology, chromosome characteristics, terminal cell density, growth pattern, residual DNA synthesis and growth in soft agar. Both cell lines exhibited human karyotype with aneuploidy and differed in their karyotype from each other.