[Comparative evaluation of treatment results of melanoblastoma of the limbs with or without perfusion chemotherapy]. / Sravnitel'naia otsenka rezul'tatov lecheniia melanoblastom konechnostei s ispol'zovaniem perfuzionnoi khimioterapii i bez nee.

The clinical picture and long-term results of the treatment of 123 patients with melanoblastoma of the limbs have been studied. 39 patients were subjected only to the surgical treatment, 84 patients with a developed tumor process were subjected to the combined treatment -- surgery with perfusional chemotherapy. 3 years survival has proved to be similar in both groups; (70.0% and 72.9%); 5 years survival has been 10% higher in the group subjected to the combined treatment (54.5% and 64.0%).

[Free dermatoplasty in melanoblastomas treated by perfusion chemotherapy]. / Svobodnaia kozhnaia plastika pri melanoblastomakh v usloviiakh perfuzionnoi khimioterapii

In the paper, the data on the immediate and late results of skin tranplantation in the complex treatment of limb melanoblastomas are reported. The latter consisted in a one-moment massive regional chemotherapy by perfusion of the extremity (iliac, femoral, brachial) with antitumor drugs, against which background melanoblastoma was excised electrosurgically, and lymphadenectomy was performed. The defect of the limb tissues, which was located on the foot or leg in 61 cases, was replaced by a free skin graft. The results of the plastic repair were followed up within the terms from 1 to 10 years.