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1.
J Pers Soc Psychol ; 118(4): 805-834, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-31916812

RESUMO

For nearly a century social scientists have sought to understand left-right ideological differences in values, motives, and thinking styles. Much progress has been made, but-as in other areas of research-this work has been criticized for relying on small and statistically unrepresentative samples and the use of reactive, self-report measures that lack ecological validity. In an effort to overcome these limitations, we employed automated text analytic methods to investigate the spontaneous, naturally occurring use of language in nearly 25,000 Twitter users. We derived 27 hypotheses from the literature on political psychology and tested them using 32 individual dictionaries. In 23 cases, we observed significant differences in the linguistic styles of liberals and conservatives. For instance, liberals used more language that conveyed benevolence, whereas conservatives used more language pertaining to threat, power, tradition, resistance to change, certainty, security, anger, anxiety, and negative emotion in general. In 17 cases, there were also significant effects of ideological extremity. For instance, moderates used more benevolent language, whereas extremists used more language pertaining to inhibition, tentativeness, affiliation, resistance to change, certainty, security, anger, anxiety, negative affect, swear words, and death-related language. These research methods, which are easily adaptable, open up new and unprecedented opportunities for conducting unobtrusive research in psycholinguistics and political psychology with large and diverse samples. (PsycINFO Database Record (c) 2020 APA, all rights reserved).


Assuntos
Hábitos , Política , Psicolinguística , Mídias Sociais , Adulto , Humanos
2.
Clin J Pain ; 35(9): 727-736, 2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31188173

RESUMO

OBJECTIVE: Inconsistent reporting of outcomes in clinical trials of treatments for Whiplash-associated Disorders (WAD) hinders effective data pooling and conclusions that can be drawn about the effectiveness of tested treatments. The aim of this study was to provide recommendations for core outcome domains that should be included in clinical trials of WAD. MATERIALS AND METHODS: A 3-step process was used: (1) A list of potential core outcome domains were identified from the published literature. (2) Researchers, health care providers, patients, and insurance personnel participated and rated the importance of each domain via a 3-round Delphi survey. A priori criteria for consensus were established. (3) Experts comprising researchers, health care providers, and a consumer representative participated in a multidisciplinary consensus meeting that made final decisions on the recommended core outcome domains. RESULTS: The literature search identified 63 potential core domains. A total of 223 participants were invited to partake in the Delphi surveys, with 41.7% completing round 1, 45.3% round 2, and 51.4% round 3. Eleven core domains met the criteria for inclusion across the entire sample. After the expert consensus meeting, 6 core domains were recommended: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life, and Pain. DISCUSSION: A 3-step process was used to recommend core outcome domains for clinical trials in WAD. Six core domains were recommended: Physical Functioning, Perceived Recovery, Work and Social Functioning, Psychological Functioning, Quality of Life, and Pain. The next step is to determine the outcome measurement instruments for each of these domains.


Assuntos
Avaliação de Resultados em Cuidados de Saúde , Projetos de Pesquisa , Traumatismos em Chicotada , Consenso , Humanos , Qualidade de Vida , Resultado do Tratamento
3.
Proc Natl Acad Sci U S A ; 116(9): 3476-3481, 2019 02 26.
Artigo em Inglês | MEDLINE | ID: mdl-30808741

RESUMO

From many perspectives, the election of Donald Trump was seen as a departure from long-standing political norms. An analysis of Trump's word use in the presidential debates and speeches indicated that he was exceptionally informal but at the same time, spoke with a sense of certainty. Indeed, he is lower in analytic thinking and higher in confidence than almost any previous American president. Closer analyses of linguistic trends of presidential language indicate that Trump's language is consistent with long-term linear trends, demonstrating that he is not as much an outlier as he initially seems. Across multiple corpora from the American presidents, non-US leaders, and legislative bodies spanning decades, there has been a general decline in analytic thinking and a rise in confidence in most political contexts, with the largest and most consistent changes found in the American presidency. The results suggest that certain aspects of the language style of Donald Trump and other recent leaders reflect long-evolving political trends. Implications of the changing nature of popular elections and the role of media are discussed.


Assuntos
Idioma , Liderança , Política , Fala , Humanos , Estados Unidos
4.
BMJ Open ; 8(11): e023664, 2018 11 25.
Artigo em Inglês | MEDLINE | ID: mdl-30478117

RESUMO

OBJECTIVE: To investigate the associations between lifestyle and vascular risk factors and changes in Alzheimer's disease (AD) biomarkers (beta-amyloid load via 11C-PiB PET, glucose metabolism via 18F-FDG PET and neurodegeneration via structural MRI) and global cognition in middle-aged asymptomatic participants at risk for AD. DESIGN: Prospective, longitudinal. SETTING: The study was conducted at New York University Langone/Weill Cornell Medical Centres in New York City. PARTICIPANTS: Seventy cognitively normal participants from multiple community sources, aged 30-60 years with lifestyle measures (diet, intellectual activity and physical activity), vascular risk measures and two imaging biomarkers visits over at least 2 years, were included in the study. OUTCOME MEASURES: We examined MRI-based cortical thickness, fluoro-deoxy-glucose (FDG) glucose metabolism and PiB beta-amyloid in AD-vulnerable regions. A global cognitive z-score served as our summary cognition measure. We used regression change models to investigate the associations of clinical, lifestyle and vascular risk measures with changes in AD biomarkers and global cognition. RESULTS: Diet influenced changes in glucose metabolism, but not amyloid or cortical thickness changes. With and without accounting for demographic measures, vascular risk and baseline FDG measures, lower adherence to a Mediterranean-style diet was associated with faster rates of FDG decline in the posterior cingulate cortex (p≤0.05) and marginally in the frontal cortex (p=0.07). None of the other lifestyle variables or vascular measures showed associations with AD biomarker changes. Higher baseline plasma homocysteine was associated with faster rates of decline in global cognition, with and without accounting for lifestyle and biomarker measures (p=0.048). None of the lifestyle variables were associated with cognition. CONCLUSIONS: Diet influenced brain glucose metabolism in middle-aged participants, while plasma homocysteine explained variability in cognitive performance. These findings suggest that these modifiable risk factors affect AD risk through different pathways and support further investigation of risk reduction strategies in midlife.


Assuntos
Doença de Alzheimer/etiologia , Doenças Vasculares/complicações , Adulto , Doença de Alzheimer/metabolismo , Doença de Alzheimer/patologia , Peptídeos beta-Amiloides/análise , Biomarcadores/análise , Biomarcadores/sangue , Encéfalo/diagnóstico por imagem , Encéfalo/metabolismo , Encéfalo/patologia , Química Encefálica , Dieta/efeitos adversos , Glucose/metabolismo , Homocisteína/sangue , Humanos , Estilo de Vida , Estudos Longitudinais , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Neuroimagem , Cidade de Nova Iorque , Tomografia por Emissão de Pósitrons , Estudos Prospectivos , Fatores de Risco , Doenças Vasculares/metabolismo , Doenças Vasculares/patologia
5.
Neurology ; 90(20): e1789-e1798, 2018 05 15.
Artigo em Inglês | MEDLINE | ID: mdl-29653991

RESUMO

OBJECTIVE: To examine in a 3-year brain imaging study the effects of higher vs lower adherence to a Mediterranean-style diet (MeDi) on Alzheimer disease (AD) biomarker changes (brain ß-amyloid load via 11C-Pittsburgh compound B [PiB] PET and neurodegeneration via 18F-fluorodeoxyglucose [FDG] PET and structural MRI) in midlife. METHODS: Seventy 30- to 60-year-old cognitively normal participants with clinical, neuropsychological, and dietary examinations and imaging biomarkers at least 2 years apart were examined. These included 34 participants with higher (MeDi+) and 36 with lower (MeDi-) MeDi adherence. Statistical parametric mapping and volumes of interest were used to compare AD biomarkers between groups at cross section and longitudinally. RESULTS: MeDi groups were comparable for clinical and neuropsychological measures. At baseline, compared to the MeDi+ group, the MeDi- group showed reduced FDG-PET glucose metabolism (CMRglc) and higher PiB-PET deposition in AD-affected regions (p < 0.001). Longitudinally, the MeDi--group showed CMRglc declines and PiB increases in these regions, which were greater than those in the MeDi+ group (pinteraction < 0.001). No effects were observed on MRI. Higher MeDi adherence was estimated to provide 1.5 to 3.5 years of protection against AD. CONCLUSION: Lower MeDi adherence was associated with progressive AD biomarker abnormalities in middle-aged adults. These data support further investigation of dietary interventions for protection against brain aging and AD.


Assuntos
Doença de Alzheimer/dietoterapia , Doença de Alzheimer/patologia , Encéfalo/metabolismo , Dieta Mediterrânea , Adulto , Doença de Alzheimer/psicologia , Encéfalo/diagnóstico por imagem , Feminino , Fluordesoxiglucose F18/farmacocinética , Humanos , Processamento de Imagem Assistida por Computador , Estudos Longitudinais , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Tomografia por Emissão de Pósitrons , Inquéritos e Questionários
6.
BMJ Open ; 8(3): e019362, 2018 03 23.
Artigo em Inglês | MEDLINE | ID: mdl-29574441

RESUMO

OBJECTIVE: To investigate the effects of lifestyle and vascular-related risk factors for Alzheimer's disease (AD) on in vivo MRI-based brain atrophy in asymptomatic young to middle-aged adults. DESIGN: Cross-sectional, observational. SETTING: Broader New York City area. Two research centres affiliated with the Alzheimer's disease Core Center at New York University School of Medicine. PARTICIPANTS: We studied 116 cognitively normal healthy research participants aged 30-60 years, who completed a three-dimensional T1-weighted volumetric MRI and had lifestyle (diet, physical activity and intellectual enrichment), vascular risk (overweight, hypertension, insulin resistance, elevated cholesterol and homocysteine) and cognition (memory, executive function, language) data. Estimates of cortical thickness for entorhinal (EC), posterior cingulate, orbitofrontal, inferior and middle temporal cortex were obtained by use of automated segmentation tools. We applied confirmatory factor analysis and structural equation modelling to evaluate the associations between lifestyle, vascular risk, brain and cognition. RESULTS: Adherence to a Mediterranean-style diet (MeDi) and insulin sensitivity were both positively associated with MRI-based cortical thickness (diet: ßs≥0.26, insulin sensitivity ßs≥0.58, P≤0.008). After accounting for vascular risk, EC in turn explained variance in memory (P≤0.001). None of the other lifestyle and vascular risk variables were associated with brain thickness. In addition, the path associations between intellectual enrichment and better cognition were significant (ßs≥0.25 P≤0.001), as were those between overweight and lower cognition (ßs≥-0.22, P≤0.01). CONCLUSIONS: In cognitively normal middle-aged adults, MeDi and insulin sensitivity explained cortical thickness in key brain regions for AD, and EC thickness predicted memory performance in turn. Intellectual activity and overweight were associated with cognitive performance through different pathways. Our findings support further investigation of lifestyle and vascular risk factor modification against brain ageing and AD. More studies with larger samples are needed to replicate these research findings in more diverse, community-based settings.


Assuntos
Doença de Alzheimer/diagnóstico por imagem , Biomarcadores , Encéfalo/patologia , Dieta Mediterrânea , Estilo de Vida , Adulto , Doença de Alzheimer/patologia , Doença de Alzheimer/prevenção & controle , Atrofia , Encéfalo/diagnóstico por imagem , Cognição , Estudos Transversais , Feminino , Humanos , Imageamento Tridimensional , Modelos Lineares , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Cidade de Nova Iorque , Fatores de Risco
7.
Musculoskelet Sci Pract ; 33: 29-34, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29073494

RESUMO

BACKGROUND: Whiplash associated disorders (WAD) result in significant personal and economic costs. Patient education and reassurance are recommended treatments for acute WAD but the information needs of patients have not been investigated. OBJECTIVES: To determine what information whiplash-injured patients believe is important to help recovery in the acute stage of injury. DESIGN: A Delphi design survey series with three rounds. METHOD: Thirty-three participants who had sustained a whiplash injury within the last three years were invited to participate. Participants were asked to provide five statements, in response to an open-ended question, regarding what they believed was the most important information to provide to patients following a whiplash injury. Nineteen patients responded and 85 statements were collected and reviewed independently by two of the authors to remove duplicates. The importance of the remaining items was rated by the participants in the second survey round. Items rated by >50% of participants as important were included in the third survey round. To be deemed key information, >80% of participants had to rate an item as important in this final round. RESULTS: Eighteen items met the criteria for key information. These points addressed four areas: assessment and treatment, recovery and symptoms, patient attitudes during treatment and relationships with health practitioners. CONCLUSIONS: The key information points endorsed by patients in this study may provide useful information to constitute a basis for reassurance and education provided to patients with WAD. The results also suggest that improved relationships between patients with whiplash and health practitioners is required.


Assuntos
Educação de Pacientes como Assunto/organização & administração , Satisfação do Paciente/estatística & dados numéricos , Traumatismos em Chicotada/diagnóstico , Traumatismos em Chicotada/terapia , Doença Aguda , Analgésicos/uso terapêutico , Técnica Delphi , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Avaliação das Necessidades , Medição da Dor , Modalidades de Fisioterapia , Recuperação de Função Fisiológica , Inquéritos e Questionários , Resultado do Tratamento
8.
Disabil Rehabil ; 40(10): 1135-1141, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-28637144

RESUMO

PURPOSE: The aims of the present study were to identify information that individuals with whiplash associated disorders (WAD) need to know in the early stages of recovery and to establish whether there is a difference between what physiotherapists and whiplash-injured patients perceive as important information. METHOD: Forty-one participants were recruited (20 whiplash-injured patients, 21 physiotherapists). Participants were asked to provide five statements to one open-ended question about what they believe is the most important information individuals with WAD need to know in the early stages of recovery. Participants provided 182 statements which were reviewed independently and organised into themes by two of the authors. RESULTS: Six key themes emerged from the statements. These included general information about whiplash injury, treatment and recovery, reassurance, provision of poor information and patients' interaction with general practitioners, maintaining daily activities, and compensation claims and litigation. Both patients and physiotherapists agreed on the type of general whiplash information that should be provided however, major differences were found with regard to information pertaining to compensation claims and litigation and maintaining daily activities. CONCLUSIONS: The findings of this study provide some insight into the type of information that WAD individuals require in the early stages of recovery. Implications for Rehabilitation The provision of reassurance can be an effective communication tool to decrease patients concerns about their injury and help strengthen the patient-health practitioner relationship. Although clinical guidelines for the management of whiplash injuries recommend that individuals must remain physically active post-injury, statements from the patient group indicate that this information is not always provided and clearly explained to patients. Keeping in line with the patient centred care approach of being responsive to patient needs and values, it is essential for health practitioners to be attentive to patients' preferences regarding the level of participation in treatment decisions. Processes need to be developed to deliver individuals with WAD accurate information regarding compensation claims so that these factors do not distract from focusing on recovery.


Assuntos
Informação de Saúde ao Consumidor/métodos , Pessoas com Deficiência , Navegação de Pacientes/métodos , Fisioterapeutas/psicologia , Traumatismos em Chicotada , Adulto , Atitude do Pessoal de Saúde , Atitude Frente a Saúde , Austrália , Tomada de Decisões , Pessoas com Deficiência/psicologia , Pessoas com Deficiência/reabilitação , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Avaliação das Necessidades , Traumatismos em Chicotada/psicologia , Traumatismos em Chicotada/reabilitação
9.
PLoS One ; 11(3): e0150556, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26982197

RESUMO

Experiments conducted during the 2004 and 2008 U.S. presidential elections suggested that mortality salience primes increased support for President George W. Bush and Senator John McCain, respectively. Some interpreted these results as reflecting "conservative shift" following exposure to threat, whereas others emphasized preferences for "charismatic" leadership following exposure to death primes. To assess both hypotheses in the context of a new election cycle featuring a liberal incumbent who was considered to be charismatic, we conducted four experiments shortly before the 2012 election involving President Barack Obama and Governor Mitt Romney. Contrary to earlier studies, there was little evidence that mortality salience, either by itself or in interaction with political orientation, affected overall candidate ratings or voting intentions. However, a significant interaction between mortality salience and system justification in some studies indicated a more circumscribed effect. The failure to "replicate" previous results in the context of this election may be attributable to disagreement among participants as to which of the candidates better represented the societal status quo.


Assuntos
Política , Adolescente , Planejamento em Desastres , Feminino , História do Século XXI , Humanos , Masculino , Terrorismo , Estados Unidos , Adulto Jovem
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