Assuntos
Artrite Gotosa , Gota , Artrite Gotosa/complicações , Extremidades , Gota/complicações , HumanosAssuntos
Alopecia em Áreas/virologia , COVID-19/virologia , SARS-CoV-2/patogenicidade , Alopecia em Áreas/diagnóstico , Alopecia em Áreas/imunologia , Antivirais/uso terapêutico , COVID-19/diagnóstico , COVID-19/imunologia , Feminino , Interações Hospedeiro-Patógeno , Humanos , Hidroxicloroquina/uso terapêutico , Pessoa de Meia-Idade , Fatores de Risco , SARS-CoV-2/efeitos dos fármacos , SARS-CoV-2/imunologia , Resultado do Tratamento , Tratamento Farmacológico da COVID-19RESUMO
Interstitial granulomatous dermatitis with arthritis (IGDA), also known as Ackerman's syndrome, is a rare cutaneous disease classically characterized by the triad of cutaneous cords, a typical histologic infiltrate mainly constituted by histiocytes and arthritis/connective tissue disease. Here we report the case of IGDA with the typical clinical and histological features in a patient affected by lupus erythematosus. In this article we underline that IGDA may have a variety of different clinical and histological features. The rope sign is typical but infrequent, while histology is usually characteristic and shows a dermal inflammatory infiltrate, with a predominance of histiocytes, localized interstitially and in a palisaded array between collagen fibres, that show signs of degeneration. Clinical and histological differential diagnoses are discussed.