[Evaluation of active immunization against viral hepatitis B in patients on hemodialysis at the National Institute of Health for the Uranium Industry in Príbram]. / Zhodnocení aktivní imunizace proti virové hepatitide typu B u pacientu hemodialyzacního pracoviste ZUNZ UP Príbram.

The authors focused their attention on one of the key problems of haemodialyzation departments--the incidence of viral hepatitis B. They tried to influence the main reservoir of the disease, i. e. the spread of the disease among dialyzed patients. In the investigated group passive and active immunization was used according to the recommended pattern. The required effect of a more permanent adequate rise of antibody levels [table: see text] was not achieved. With this corresponded also the clinical correlation, i. e. the incidence of manifest hepatitis B in dialyzed patients. It will be necessary to elaborate another method of immunization with regard to the impaired immunity system of these patients.

E rosettes in the uranium miners with lung cancer.

Rosette forming cells (RFC) were evaluated in the peripheral blood of healthy persons, patients with lung cancer and chronic bronchitis. Simultaneously the levels of RFC in persons with and without radiation exposure were compared. Two types of rosettes were enumerated: 1) lymphocytes binding 1 or 2 sheep red blood cells (SRBC), 2) lymphocytes binding 3 or more SRBC. Then the sum of both types was calculated. The patients with lung cancer were divided according to the TNM classification and histological types. The relative and absolute numbers of RFC in 1 microliter of peripheral blood proved depressed capacity of peripheral T-lymphocytes to form rosettes not only in patients with cancer or chronic bronchitis but also in controls with radiation exposure. Furthermore, there was established that the control group with radiation exposure was not different from the patients with cancer or chronic bronchitis.