RESUMO
Cylindrospermopsin, a hepatotoxin produced by cyanobacteria, has been unambiguously detected in cyanobacteria collected from a recreational lake in the Wellington region of New Zealand. To our knowledge this is the first report of cylindrospermopsin in New Zealand. Cylindrospermopsin and several microcystins were identified by reversed phase high-performance liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry (LC-MS/MS) using an atmospheric-pressure ionization source and an ionspray interface. The presence of cylindrospermopsin in New Zealand highlights the risk of direct cyanobacterial toxin exposure in recreational waters.
Assuntos
Cianobactérias/patogenicidade , Uracila/análogos & derivados , Uracila/análise , Alcaloides , Toxinas Bacterianas , Toxinas de Cianobactérias , Água Doce/análise , Espectrometria de Massas , Nova ZelândiaRESUMO
A spiroimine, gymnodimine B (1), was isolated from cells recovered by filtration from cultures of a marine dinoflagellate, Gymnodinium sp. Its structure was identified by one- and two-dimensional NMR spectroscopy and mass spectrometry. Gymnodimine B is similar in structure to gymnodimine (2) but contains an exocyclic methylene at C-17 and an allylic hydroxyl group at C-18.
