1.
Chem Commun (Camb)
; 51(64): 12867-70, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26169627
RESUMO
A heterocyclic, sp(3)-rich chemical scaffold was synthesised in just 6 steps via a highly regio- and diastereo-selective tandem nitrone formation/intramolecular nitrone-alkene [3+2] cycloaddition reaction. A library of 543 lead-like compounds based on the scaffold core has been produced.