[Measures for the combined therapy and prevention of dermatoses occurring in workers in contact with organophosphorus pesticides]. / K voprosu o merakh kompleksnoi terapii i profilaktiki dermatozov, voznikaiushchikh u rabochikh, kontaktiruiushchikh s fosfororganicheskimi pestitsidami.

Allergenic and photosensitizing effects of organophosphorus pesticides (OPP) have been detected, as well as their destructive effect on the skin cell ultrastructure, on the body metabolism and enzymic systems, and the inhibitory effect on cholinesterase activity. Pesticide-induced changes in polyunsaturated fatty acids (PUFA) are significant in the mechanism of dermatoses development. The complex of treatment-and-prophylaxis measures includes regular dermatologic check-ups and limitation of the number of subjects handling OPP. Subjects in whom premorbid shifts have been detected, should be followed up. The therapy and prevention of the dermatoses developing as a result of exposure to pesticides may be effectively carried out with antioxidants, amino acids, vitamins, etc.; diets with the optimal PUFA-tocopherol ratio are advisable. Overalls with multiple protective physicochemical characteristics, filtering respirators and such are recommended.

[Occupational phytodermatoses and their prevention]. / K voprosu o professional'nykh fitodermatozakh i ikh profilaktike.

The growing employment of the population in agriculture and wide use of plants in industry lead to an increase in the incidence rate of phytodermatoses. The strongest allergens are Ambrosia and Artemisia pollen, as well as exotic trees wood. Measures for the prevention of occupational phytodermatoses are an integral part of the complex program for the improvement of specialized medical care in the rural regions. Patients suffering from occupational phytodermatoses should be subjected to regular check-ups.