[Complex assessment of the production of 3 variants of interleukin-1 by human peripheral blood monocytes]. / Kompleksnaia otsenka produktsii 3 variantov interleikina-1 monotsitami perifericheskoi krovi cheloveka.

In vitro production of intracellular, membrane-associated and secreted interleukin-1 was investigated by peripheral blood monocytes from healthy donors. Activity of three IL-1 variants was assayed by the proliferation of responsive C3H/HeJ mouse thymocytes. Complex evaluation of IL-1 pools production by human PBM would provide a key to a better understanding of various diseases pathogenesis.