Assuntos
Assistência Progressiva ao Paciente/tendências , Instituições de Cuidados Especializados de Enfermagem/tendências , Prestação Integrada de Cuidados de Saúde , Acessibilidade aos Serviços de Saúde , Relações Interinstitucionais , Programas de Assistência Gerenciada , Sistema de Pagamento Prospectivo , Estados UnidosRESUMO
Total fatty acids and the proportions of methyl esters of individual fatty acids were measured in mouse milk. Pregnant mice were fed either a high fat (HF) diet or a low fat (LF) diet from 14 days of gestation. After parturition, each dam was milked once a day for a period of 18 days. The mean total fatty acid concentration over the entire study period was 110 mg/g of milk (approximately 11.7% fat as triglyceride) for both dietary treatment groups. During days 2 to 6 postpartum, the mean total fatty acid concentration for dams fed HF diet was lower than for the LF group. Although the concentration of total fatty acids of mouse milk was not affected by the level of dietary fat fed to the dam, several variations in the proportions of individual fatty acids were observed.
Assuntos
Gorduras na Dieta/administração & dosagem , Lipídeos/análise , Leite/análise , Animais , Animais Recém-Nascidos/metabolismo , Ésteres/análise , Ácidos Graxos/análise , Feminino , Camundongos , Camundongos Endogâmicos ICR , GravidezRESUMO
NIH/Swiss mice were used to study the effects of exercise on bleomycin-induced pulmonary toxicity. After a 2-week exercise acclimation program the mice were treated with bleomycin sc twice a week and swim-exercised for 1 hour three times a week for 6 weeks. Based on higher mortality and significant weight loss in the exercise-drug-treated mice and a comparison of histological data, it is concluded that exercise exacerbates the toxicity of bleomycin.
