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Am J Forensic Med Pathol ; 41(3): 143-151, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32379077

RESUMO

As a result of the 2019 novel human coronavirus (COVID-19) global spread, medical examiner/coroner offices will inevitably encounter increased numbers of COVID-19-infected decedents at autopsy. While in some cases a history of fever and/or respiratory distress (eg, cough or shortness of breath) may suggest the diagnosis, epidemiologic studies indicate that the majority of individuals infected with COVID-19 develop mild to no symptoms. Those dying with-but not of-COVID-19 may still be infectious, however. While multiple guidelines have been issued regarding autopsy protocol in cases of suspected COVID-19 deaths, there is some variability in the recommendations. Additionally, limited recommendations to date have been issued regarding scene investigative protocol, and there is a paucity of publications characterizing COVID-19 postmortem gross and histologic findings. A case of sudden unexpected death due to COVID-19 is presented as a means of illustrating common autopsy findings, as well as diagnostic and biosafety considerations. We also review and summarize the current COVID-19 literature in an effort to provide practical evidence-based biosafety guidance for medical examiner-coroner offices encountering COVID-19 at autopsy.


Assuntos
Autopsia/normas , Betacoronavirus/isolamento & purificação , Contenção de Riscos Biológicos/normas , Infecções por Coronavirus/mortalidade , Infecções por Coronavirus/patologia , Pneumonia Viral/mortalidade , Pneumonia Viral/patologia , Betacoronavirus/genética , COVID-19 , Centers for Disease Control and Prevention, U.S. , Feminino , Humanos , Pessoa de Meia-Idade , Práticas Mortuárias/métodos , Práticas Mortuárias/normas , Pandemias , Reação em Cadeia da Polimerase em Tempo Real/normas , SARS-CoV-2 , Triagem , Estados Unidos
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