A comparative clinical study of Solcoseryl Eye-Gel and Cysteine Eye-Gel 2.4% in the treatment of foreign-body injuries of the cornea.

Solcoseryl, a protein-free haemodialysate, promotes tissue regeneration and improves utilization of oxygen in the cell. In a randomized, double-blind, clinical study, Solcoseryl Eye-Gel was compared with Cysteine Eye-Gel in the treatment of foreign-body injuries of the cornea in a total of 99 eyes. In order to facilitate objective evaluation of the effects of the treatment, the area of the lesion before the start of treatment and on the following day was determined by means of slit-lamp photographs. Healing of the lesion and relative reduction of the area of the wound were observed much more frequently in the group treated with Solcoseryl Eye-Gel than in the reference group. Maculae corneae after the end of the treatment were significantly less frequent under Solcoseryl Eye-Gel than under Cysteine Eye-Gel. Teh tolerability of the test preparation was good; an itching sensation was reported in only 2 cases. Under Cysteine Eye-Gel, on the other hand, a burning sensation was reported by a number of patients and very fine deposits in the epithelium were also observed in a few cases. Thus complete closure of the epithelium over the lesion after 1 day was observed much more frequently in the group of patients treated with Solcoseryl Eye-Gel than in the reference group (63 vs. 53%).

[Symptomatology of a primary intraorbital meningioma of the optic nerve]. / Zur Symptomatologie eines primär intraorbitalen Meningiomes des Nervus opticus.

Report on an 18-year-old man with a histologically confirmed intraorbital meningioma (transitional type) of the right optic nerve. The symptoms were slowly progressive loss of vision with central scotoma and pallor of the disk, without proptosis or disturbance of eye motility. Computer tomography performed preoperatively did not permit the differential diagnosis of glioma.