1.
Phys Chem Chem Phys
; 17(39): 26084-92, 2015 Oct 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26377043
RESUMO
The specific features of structural self-organization of C60 fullerene and antitumor drug cisplatin (Cis) in physiological solution (0.9% NaCl) have been investigated by means of small-angle neutron scattering, scanning electron and atomic force microscopies, as well as isothermal titration calorimetry, dynamic light scattering and UV-Vis spectroscopy. The formation of C60 + Cis complexes, has been reported, unveiling the mechanism of medico-biological synergy observed during administration of the mixture of these drugs.