1.
Chem Commun (Camb)
; 56(88): 13551-13554, 2020 Nov 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33048065
RESUMO
A practical copper and palladium co-catalyzed highly regio-selective hydroarylation of terminal 1,3-dienes has been developed. This chemistry afforded the terminal alkenyl group containing products, which are a kind of versatile precursor for organic synthesis, from 1,3-dienes by a practical one-step reaction. With good functional group tolerance, this protocol could be used to make a series of bio-active compounds using readily accessible starting materials. The mechanism of this reaction was explored by control experiments and kinetics studies.