Evidence in Support of the Border-Ownership Neurons for Representing Textured Figures.

We presented one eye with a monocular-boundary-contour (MBC) square, created by phase-shifting a central region of grating relative to a larger uniform grating surround, and the fellow eye with the larger uniform grating. In addition, the grating within the MBC region was rendered with lower contrast relative to the remaining stimulus. Despite this, we found the lower contrast MBC region dominated the perceived cyclopean contrast, with the corresponding region in the fellow eye being suppressed. Secondly, we found for dichoptic stimuli with half-images having square grating regions of different BC strengths, the interocular BC strength ratio determined the perceived contrast of the cyclopean square. Thirdly, we found perceived spatial phase of the cyclopean square was dominated by the spatial phase of the MBC half-image. Altogether, these psychophysical findings provided evidence for a border-to-interior representation strategy, that constructing surface begins at the boundary contour (BC), in binocular contrast and phase integration.

Perceptual mechanisms underlying amodal surface integration of 3-D stereoscopic stimuli.

The visual system can represent a partially occluded 3-D surface from images of separated surface segments. The underlying amodal surface integration process accomplishes this by amodally extending each surface segment behind the occluder (amodal surface extension) and integrating the extended surfaces to form a whole surface representation. We conducted five experiments to investigate how depth cues, such as binocular disparity, half-occlusion, and monocular depth cues (T-junctions and L-junctions), contribute to amodal surface extension, and how the geometrical relationship and image similarity among the surface segments affect surface integration. This was achieved by having observers adjust the stereoscopic depth and slant of a comparison stimulus to match those of the tested 3-D stimulus. We found that both binocular disparity and half-occlusion cues are used to determine border-ownership assignment of surface segments and for amodal surface extension. We also found that separated surface segments need to have the same luminance contrast-polarity for them to be integrated as a whole surface. Finally, we found that having the same motion direction, minimum misalignment between boundary contours, and proximity among separated segments facilitate their integration. Overall, our findings reveal a set of "perceptual factors" for amodal surface integration, which arguably reflects our visual system's built-in knowledge of the regularities in natural scenes.

A push-pull treatment for strengthening the 'lazy eye' in amblyopia.

Almost all individuals exhibit sensory eye dominance, one neural basis of which is unequal interocular inhibition. Sensory eye dominance can impair binocular functions that depend on both excitatory and inhibitory mechanisms. We developed a 'push-pull' perceptual learning protocol that simultaneously affects the excitatory and inhibitory networks to reduce sensory eye dominance and improve stereopsis in adults with otherwise normal vision. The push-pull protocol provides a promising clinical paradigm for treating the extreme sensory eye dominance in amblyopia ('lazy eye'). The prevailing standard of care does not directly treat sensory eye dominance; instead, selected excitatory functions in the amblyopic eye are stimulated while the strong eye is patched, on the assumption that recovery of the weak eye's excitatory functions rebalances the eyes. Patching the strong eye does not directly address interocular inhibition; in contrast, the push-pull protocol by design excites the weak eye, while completely inhibiting the strong eye's perception to recalibrate the interocular balance of excitatory and inhibitory interactions. Here, we show that three adult amblyopes who trained on the push-pull protocol gained longstanding improvements in interocular balance and stereopsis. Our findings provide a proof-of-concept and evidence that push-pull learning leads to long-term plasticity.

Revealing boundary-contour based surface representation through the time course of binocular rivalry.

We varied the surface boundary-contour properties of binocular rivalry (BR) stimuli to measure the rivalry percept as a function of stimulus duration. Experiment 1 compared perception from BR stimuli with monocular boundary contour (MBC) and binocular boundary contour (BBC). We found global dominance is achieved with stimulus duration as short as 30ms for the MBC rivalry stimuli, whereas it takes more than 150 ms for the BBC rivalry stimuli. This shows that global dominance can occur rapidly in the absence of a corresponding boundary contour in one half-image. Experiment 2 measured the detection of a monocular Gabor probe located centrally on a 1.5° versus 3.0° MBC rivalry stimulus. We found reliable binocular suppression is observed earlier with the 1.5° MBC stimulus, presumably because of the probe being spatially located nearer to the boundary contour. These findings, in conjunction with those in Su et al. (2011), support the notion that the representation of the dominant surface begins at the MBC and spreads toward the center of the image.

Seeing grating-textured surface begins at the border.

Two experiments were conducted to reveal that the human visual system represents grating texture surface using a border-to-interior strategy. This strategy dictates that the visual system first registers the surface boundary contour and then sequentially spreads texture from the border to the interior of the image. Our experiments measured the perceived grating texture surface at various stimulus durations after the onset of a grating texture image. We found that the grating texture is initially seen near the boundary contours, with eventual spreading inward to the center of the image. To quantify the observation, the extent of the texture spreading from the boundary contour is measured as a function of the stimulus duration (30-500 ms). This allows us to analyze the texture spreading in retinal and cortical distances, based on human fMRI studies of the cortical magnification factor in cortical areas V1-V4, and to derive the spreading speed. We found that the spreading speed is constant when scaled according to the cortical distance. Similar findings are obtained no matter whether the grating texture image is presented monocularly or dichoptically, suggesting the generality of the border-to-interior strategy for representing surfaces.

The magnitude and dynamics of interocular suppression affected by monocular boundary contour and conflicting local features.

A monocular boundary contour (MBC) rivalry stimulus has two half-images, a homogeneous grating and the same homogeneous grating with an additional disc region. The outline/frame of the MBC disc is created by relative phase-shift, or orientation-difference. We found the increment contrast threshold and reaction time to detect a monocular Gabor probe elevated on the homogeneous half-image pedestal. The interocular suppression begins as early as 80ms upon stimulus onset. Moreover, the suppression magnitude is larger when the MBC disc is defined by orientation-difference rather than phase-shift, revealing the suppression caused by competing local features in addition to MBC.

Boundary contour-based surface integration affected by color.

The visual system represents occluded surfaces by integrating the visible and partially occluded fragments with reliance on surface boundary contours. Does surface integration also depend on color similarity? Using displays with aligned images, we found the visual system has a preference to integrate images with the same color to form occluded surfaces and construct illusory occluding surfaces. This results in enhanced shape discrimination of briefly presented stimuli, and a tendency to perceive global motion of the integrated fragments. The contribution of color to surface integration is observed both in equiluminous setting and in non-equiluminous setting, where achromatic contrast exists.