Metástasis dural como manifestación inicial de cáncer de próstata / Dural metastasis as the first manifestation of prostate cancer

Las metástasis del cáncer de próstata en las meningesintracraneales son raras y con frecuencia son confundidas con meningiomas, hematomas epiduraleso subdurales crónicos. Usualmente se presentan en pacientes con diagnóstico oncológico conocido en estadios avanzados de la enfermedad y solo en algunos raros casos sus manifestaciones han precedido a la detección del tumor primario. La presentación clínica es inespecífica, sin embargo, por la afinidad de estos tumores por la base del cráneo, constituye un diagnóstico diferencial del compromiso de pares craneales en varones mayores de 70 años. El tratamiento de estas lesiones no ha sido estandarizado y dentro de las opciones terapéuticas están la resección quirúrgica, quimioterapia, radioterapia o la combinación de estas medidas y aún así la supervivencia es corta. Se presenta el caso de un varón de 77 años cuya manifestación inicial del cáncer de próstata fue la sintomatología producida por una lesión metastásica en laduramadre, confirmada por histopatología. Se revisan los aspectos epidemiológicos, clínicos y de imagen más sobresalientes de las metástasis meníngeas del cáncer de próstata (AU)

Metastases of prostate cancer to intracranial meninges are rare and often confused with meningiomasor chronic subdural hematomas. These usually occurin patients with a known cancer diagnosis in advanced stages of the disease, and only in some rare cases doits manifestations precede the detection of the primary tumour. The clinical presentation is unspecific. However, due to the affinity of this tumour for the base of theskull, it must be included in the differential diagnosis of men over 70 years of age with cranial nerve palsy. The treatment of these lesions has not been standardized. With in the therapeutic options we find surgical resection, chemotherapy, radiotherapy or a combination of these measures, and yet survival is poor.We present the case of a 77 year old male patient whose initial symptoms of prostate cancer were causedby a metastatic lesion to the dura, confirmed by histopathology. We also review the epidemiological, clinical and imaging highlights of this condition (AU)

[Dural metastasis as the first manifestation of prostate cancer]. / Metástasis dural como manifestación inicial de cáncer de próstata.

Metastases of prostate cancer to intracranial meninges are rare and often confused with meningiomas or chronic subdural hematomas. These usually occur in patients with a known cancer diagnosis in advanced stages of the disease, and only in some rare cases do its manifestations precede the detection of the primary tumour. The clinical presentation is unspecific. However, due to the affinity of this tumour for the base of the skull, it must be included in the differential diagnosis of men over 70 years of age with cranial nerve palsy. The treatment of these lesions has not been standardized. Within the therapeutic options we find surgical resection, chemotherapy, radiotherapy or a combination of these measures, and yet survival is poor. We present the case of a 77 year old male patient whose initial symptoms of prostate cancer were caused by a metastatic lesion to the dura, confirmed by histopathology. We also review the epidemiological, clinical and imaging highlights of this condition.