CAD-CAM Hollow Obturator Prosthesis: A Technical Report.

An obturator with a hollow bulb can decrease the overall weight of the prosthesis, stress on the underlying tissues, and patient discomfort. Although many techniques and materials have been proposed in the literature for hollowing the obturator prosthesis, they are often time consuming and technique sensitive. This proposed technique used an open-source software program to hollow a digital design of a solid obturator base from a commercially available software in one single convenient step. The hollowing process allowed precise control of prosthesis thickness at the hollow space area for desirable hermetic seal and prosthesis strength.

Use of intraoral scan for implant-supported dental prosthesis to design and fabricate a CAD-CAM verification device: A dental technique.

This technical report describes a digital process to design and fabricate a verification device directly from an intraoral scan for nonsegmental implant-supported dental prostheses. By using an open source computer-aided design software program, this technique provides an economical option for dentists and dental laboratory technicians to fabricate a computer-aided design and computer-aided manufacturing (CAD-CAM) verification device. This technique is particularly beneficial for a long scanning span and large edentulous space with multiple scan bodies, and a verification device can be used to confirm the accuracy of a CAD-CAM implant definitive cast.

Use of an open-source CAD software program and additive manufacturing technology to design and fabricate a definitive cast for retrofitting a crown to an existing removable partial denture.

This technical report describes a digital process for designing and fabricating a stackable definitive cast and die system to facilitate the fabrication of a new surveyed crown to retrofit to a removable partial denture (RPD). By using an open-source computer-aided design (CAD) software program, this technique provides an economical option for dental clinicians and laboratory technicians to use intraoral scans and design a stackable definitive cast and die system with minimal financial investment in the CAD software. In addition, this technique provides the advantage of a conventional indirect technique in that it can create a definitive cast with an RPD clasp assembly ready for the dental technician to properly contour the new surveyed crown, but without the need for the patient to be without the RPD during the process.

The Role of NF mRNA and Calpain in NF Reduction of Acrylamide Neuropathy / 生物医学与环境科学（英文）

The purpose of this study was to study the role of neurofilament (NF) mRNA and calpain in NF reduction of acrylamide (ACR) neuropathy. Male Wistar adult rats were injected i.p. every other day with ACR (20 mg/kg·bW or 40 mg/kg·bW) for 8 weeks. NF mRNA expression was detected using RT-PCR and the calpain concentration was determined using western blot analysis. The NF mRNA expression significantly decreased while the level of m-calpain and μ-calpain significantly increased in two ACR-treated rats groups regardless of the ACR dose. The light NF (NF-L) protein expression was significantly correlated with NF-L mRNA expression. Combined with previous data, the concentrations of three NF subunits were negatively correlated with the calpain levels. These findings suggest that NF-L mRNA and calpain mediated the reduction in NF of ACR neuropathy.

Analyzing the factors of influencing the musculoskeletal disorders of greenhouse vegetable farmers / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To study the prevalence of musculoskeletal disorders (MSDs) among greenhouse vegetable farmers and to explore the risk factors of MSDs.</p><p><b>METHODS</b>A household questionnaire survey was conducted to investigate 203 greenhouse vegetable farmers and 127 non-greenhouse vegetable farmers in February, 2011.</p><p><b>RESULTS</b>The one-year prevalence rates of MSDs were 70.0% and 33.9% among greenhouse vegetable farmers and non-greenhouse vegetable farmers, respectively. The three main positions of MSDs in greenhouse farmers were low back, knee (s) and shoulder (s). Age, working years, body weight and usage of rolling machine were statistically associated with MSDs of greenhouse farmers, ORadj values were 1.17, 1.82, 1.08 and 0.07, respectively.</p><p><b>CONCLUSIONS</b>The prevalence of MSDs is high in greenhouse workers. Low back pain, knee (s), and shoulder (s) disorders are the main disorders. Age, working years, body weight and usage of rolling machine are main risk factors for the development of MSDs in greenhouse farmers.</p>