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1.
World Neurosurg ; 154: e168-e175, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34245879

RESUMO

BACKGROUND: Functional status of cerebrospinal fluid (CSF) diversion procedure for hydrocephalus is difficult to assess on several occasions. We report the use of serial ultrasonographic measurement of optic nerve sheath diameter (ONSD) to assess the functional status of CSF diversion procedures in patients with hydrocephalus. METHODS: In this prospective observational study, ultrasonographic ONSD measurement was performed preoperatively, on postoperative days 1, 3, and 7 (n = 51 at each time point) and at follow-up (n = 31) in patients undergoing ventriculoperitoneal shunt or endoscopic third ventriculostomy for hydrocephalus. Change in ONSD values during first week after CSF diversion procedure and at follow-up were correlated with ventriculoperitoneal shunt/ETV function. RESULTS: ONSD ≥5.5 mm strongly correlated with clinical and imaging features of raised ICP (P < 0.001). Mean ONSD progressively decreased in the postoperative period and was the lowest on postoperative day 7 (P < 0.001) with >95% of patients having ONSD <5.5 mm at that time point. At follow-up (median, 12 months; n = 31), ONSD had further reduced in 78.6% of patients. All 3 patients with shunt dysfunction had an increase in the ONSD value compared with that on postoperative day 7. CONCLUSIONS: ONSD measurement on postoperative day 7 after CSF diversion correlates well with early surgical outcome but decreases further in many patients at a follow-up of 12 months. Rise in postoperative day 7 ONSD at follow-up correlates with failure of the CSF diversion procedure.


Assuntos
Derivações do Líquido Cefalorraquidiano , Hidrocefalia/cirurgia , Nervo Óptico/diagnóstico por imagem , Derivação Ventriculoperitoneal/métodos , Adolescente , Adulto , Idoso , Criança , Feminino , Seguimentos , Humanos , Pressão Intracraniana , Masculino , Pessoa de Meia-Idade , Período Pós-Operatório , Estudos Prospectivos , Resultado do Tratamento , Ultrassonografia , Ventriculostomia , Adulto Jovem
3.
Br J Neurosurg ; 34(1): 98-101, 2020 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29446979

RESUMO

Introduction: Synovial sarcoma is a rare mesenchymal malignant neoplasm that accounts for less than 10% of soft tissue sarcomas. About 95% of the sarcomas occur in the extremities. Primary synovial sarcomas of the spine are a rare tumor arising from the paravertebral regions, paraspinal muscles or epidural spaces.Purpose: To report an atypical radiological presentation of synovial sarcoma of the thoracic spine mimicking a nerve sheath tumor in an elderly adult and describe the management with review of the literature.Clinical presentation: A forty-six-year-old lady presented with clinical features of a thoracic intradural extramedullary cord compression at T7 level. She was Nurick grade 4 at presentation. MRI of the Thoracic spine with whole spine screening showed a contrast enhancing intradural extramedullary tumor at the T7-8 level; the tumor was exiting out through the left T7-8 neural foramina with foraminal widening. The possibility of a schwannoma was considered.Intervention: She underwent a T7-8 laminectomy and total excision of the tumor followed by posterior fusion. The biopsy was reported as synovial sarcoma. She subsequently underwent radiation and chemotherapy. She had marked improvement in her Neurological status and remained disease free at six months follow-up.Conclusion: Synovial sarcoma of the spine is a rare mesenchymal malignant neoplasm. One needs to consider Synovial sarcoma as one of the differential diagnosis of intradural tumors of the spine.


Assuntos
Diagnóstico Diferencial , Neurilemoma/patologia , Sarcoma Sinovial/patologia , Sarcoma Sinovial/cirurgia , Neoplasias da Coluna Vertebral/patologia , Neoplasias da Coluna Vertebral/cirurgia , Quimiorradioterapia , Terapia Combinada , Feminino , Humanos , Laminectomia , Imageamento por Ressonância Magnética , Pessoa de Meia-Idade , Neoplasias de Bainha Neural/diagnóstico por imagem , Neoplasias de Bainha Neural/patologia , Neurilemoma/diagnóstico por imagem , Procedimentos Neurocirúrgicos/métodos , Sarcoma Sinovial/diagnóstico por imagem , Neoplasias da Medula Espinal/diagnóstico por imagem , Neoplasias da Medula Espinal/patologia , Neoplasias da Medula Espinal/cirurgia , Neoplasias da Coluna Vertebral/diagnóstico por imagem
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