1.
Pharmazie
; 57(7): 489-90, 2002 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12168534
RESUMO
Treatment of spore suspension of Cephalosporium acremonium ATCC 48272 with UV rays and N-methyl-N-nitro-N-nitrosoguanidine (NTG) induced mutants capable of producing higher yields of cephalosporin C. Antibiotic yield was improved from 630 micrograms/ml to 1995 micrograms/ml of the broth resulting in a high yielding mutant.