RESUMO
Although anemia frequently occurs in poststreptococcal acute glomerulonephritis (PSAGN), severe anemia is rare. We report severe normocytic, normochromic anemia (hematocrit, 19.8%) in PSAGN in a 6-year-old girl with edema, macrohematuria, and proteinuria for 1 month. The potential causes of severe anemia found in this case were: 1) longer duration of massive hematuria from onset of macrohemauria to treatment, 2) a level of erythropoietin much lower than that in cases of iron deficiency anemia, and 3) hemodilution. We speculate that these factors combined to cause an unusual case of severe anemia in PSAGN.
Assuntos
Anemia/complicações , Anemia/microbiologia , Glomerulonefrite/complicações , Glomerulonefrite/microbiologia , Infecções Estreptocócicas/complicações , Doença Aguda , Anemia/patologia , Criança , Feminino , Humanos , Índice de Gravidade de DoençaRESUMO
Kawasaki disease (KD) is a multisystem disorder of unknown origin and usually associated with thrombocytosis. The authors describe a case of KD exhibiting thrombocytopenia with markedly large platelets. Among the 173 KD cases, 3 cases exhibited thrombocytopenia. One of these showed cardiac involvement with giant aneurysm of the coronary artery (33%), while only 1 of the remaining 170 cases exhibited cardiac involvement without thrombocytopenia (0.6%). The authors believe that it is important for clinicians to be aware that thrombocytopenia may occur during the course of KD and that this may be a more active condition when compared with thrombocytosis.
