1.
Chem Asian J
; 14(17): 2953-2957, 2019 Sep 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31321878
RESUMO
This paper describes the synthesis of protein microtube motors having a urease interior surface and highlights their nonbubble-propelled behavior driven by enzymatic reaction (ureaâNH3 and CO2 ). The precursor microtubes were prepared by layer-by-layer assembly using a track-etched microporous polycarbonate membrane. Immobilization of a urease on the internal wall was accomplished using avidin-biotin interaction. The tubules swam smoothly in an aqueous media containing a physiological concentration of urea. Each tubule was rotating laterally while moving forward. It is remarkable that the microtubes were digested completely by proteases, demonstrating perfect biodegradability.