RESUMO
Routine screening for sexually transmitted diseases in new patients attending the Genitourinary Clinic in Stoke-on-Trent includes a culture for Mycoplasma hominis (MH) and Ureaplasma urealyticum (UU). A retrospective study was carried out on 400 female patients to ascertain whether there were any significant differences between the group positive for MH and UU and the negative control group. The positive group were found to be younger on average, but to have similar sexual histories to the negative control group. An association was found between the presence of genital mycoplasmas and Gardnerella vaginalis. An odourous vaginal discharge was more common in the positive group. Erythromycin was ineffective in eradicating the organisms in 62.5% of patients with MH, and 70% of those with UU. Continuing work is required to identify those women in whom the presence of MH or UU could have pathogenic effects. Treatment regimens for this group of women need to be carefully reassessed, in the light of increasing antibiotic resistance.
Assuntos
Doenças dos Genitais Femininos/microbiologia , Infecções por Mycoplasma/microbiologia , Mycoplasma/isolamento & purificação , Infecções por Mycoplasmatales/microbiologia , Ureaplasma/isolamento & purificação , Adulto , Fatores Etários , Aminas/análise , Candidíase Vulvovaginal/complicações , Eritromicina/uso terapêutico , Feminino , Gardnerella vaginalis/isolamento & purificação , Doenças dos Genitais Femininos/tratamento farmacológico , Infecções por Haemophilus/complicações , Humanos , Infecções por Mycoplasma/complicações , Infecções por Mycoplasma/tratamento farmacológico , Infecções por Mycoplasmatales/complicações , Infecções por Mycoplasmatales/tratamento farmacológico , Oxitetraciclina/uso terapêutico , Estudos RetrospectivosRESUMO
A 58 year old man presented with what seemed to be a simple penile lesion, but which on subsequent histological examination proved to be a malignant melanoma. The lesion was excised by circumcision. No further treatment was considered to be necessary.
Assuntos
Melanoma/patologia , Neoplasias Penianas/patologia , Circuncisão Masculina , Humanos , Masculino , Melanoma/cirurgia , Pessoa de Meia-Idade , Neoplasias Penianas/cirurgiaRESUMO
In a double-blind study of the treatment of vaginal candidiasis, miconazole nitrate gave a cure-rate of 88 per cent. (29 out of 33) compared with 58 per cent. (21 out of 36) using chlordantoin. Although approximately two-thirds of the patients who responded did so to a 10-day course of treatment, the different rates of cure with these preparations at this stage were not statistically significant. However, when a second course of treatment was given to those women who still had proven candidiasis, the overall cure-rate with miconazole was significantly greater than that with chlordantoin.
