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1.
J Pharm Bioallied Sci ; 15(Suppl 2): S1065-S1068, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37694067

RESUMO

Introduction: Extraction of the tooth often leads to crestal bone loss. It is difficult for clinicians to decide on the technique of extraction. Many studies on flap and flapless have led to confusion. Hence it becomes necessary to conduct this study to show the efficient ridge preservation technique. Materials and Methods: Twenty patients were selected for this study. It was divided into the flap and flapless groups. In group A, the flap was elevated, tooth extraction was undertaken, the socket was cleaned, a graft was placed, a barrier was placed, and a suture was placed. In group B all the procedures were the same but without flap elevation. After surgery, clinical and radiographical parameters were recorded. Result: Flapless technique showed a better result in bone preservation. There was a low vertical bone loss in the flapless technique. Conclusion: Both techniques showed bone loss. But the flapless technique gave better results.

2.
J Pharm Bioallied Sci ; 13(Suppl 2): S1410-S1413, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-35018000

RESUMO

BACKGROUND: Diabetes is seen to be associated with increased rate of failure of implants. The implant failure can be categorized as ailing, failing, and failed implants. The review of literature did not form any consensus on the effect of diabetes on the implant success rates. The reason we found was many confounding factors and nonconsideration of glycemic status of diabetic patients. Hence, in our study, we eliminated the confounding factors and took glycemic index in consideration. MATERIALS AND METHODS: Forty-six participants were included in this study, out of which 26 were nondiabetic and 20 diabetic. Diabetics were further divided into two groups based on the HBA1C values, as controlled and uncontrolled diabetics. RESULTS: We found that the uncontrolled diabetics had highest rate of implant failure as compared to other two groups. Furthermore, the controlled diabetics and nondiabetics had similar implant successes and failure rates. CONCLUSION: This suggests that controlled diabetics are comparable to nondiabetics in terms of implant success rates.

3.
Theor Appl Genet ; 134(1): 367-379, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33079215

RESUMO

Fusarium wilt (FW) and sterility mosaic diseases (SMD) are key biotic constraints to pigeonpea production. Occurrence of these two diseases in congenial conditions is reported to cause complete yield loss in susceptible pigeonpea cultivars. Various studies to elucidate genomic architecture of the two traits have revealed significant marker-trait associations for use in breeding programs. However, these DNA markers could not be used effectively in genomics-assisted breeding for developing FW and SMD resistant varieties primarily due to pathogen variability, location or background specificity, lesser phenotypic variance explained by the reported QTL and cost-inefficiency of the genotyping assays. Therefore, in the present study, a novel approach has been used to develop a diagnostic kit for identification of suitable FW and SMD resistant lines. This kit was developed with 10 markers each for FW and SMD resistance. Investigation of the diversity of these loci has shown the role of different alleles in different resistant genotypes. Two genes (C.cajan_03691 and C.cajan_18888) for FW resistance and four genes (C.cajan_07858, C.cajan_20995, C.cajan_21801 and C.cajan_17341) for SMD resistance have been identified. More importantly, we developed a customized and cost-effective Kompetitive allele-specific PCR genotyping assay for the identified genes in order to encourage their downstream applications in pigeonpea breeding programs. The diagnostic marker kit developed here will offer great strength to pigeonpea varietal development program, since the resistance against these two diseases is essentially required for nominating an improved line in varietal release pipeline.


Assuntos
Cajanus/genética , Resistência à Doença/genética , Fusarium/patogenicidade , Doenças das Plantas/genética , Infertilidade das Plantas/genética , Alelos , Genes de Plantas , Marcadores Genéticos , Genótipo , Técnicas de Genotipagem , Mutação INDEL , Fenótipo , Doenças das Plantas/microbiologia , Polimorfismo de Nucleotídeo Único , Seleção Genética
4.
J Pharm Bioallied Sci ; 12(Suppl 1): S613-S618, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33149530

RESUMO

BACKGROUND: There is emerging interest and increasing amount of evidence that support the interrelationship between periodontitis and systemic conditions. Epidemiological and microbiological-immunological studies have lent credence to the concept that periodontal disease may be a separate risk factor for cardiovascular disease, cerebrovascular disease, and respiratory disease, as well as preterm delivery of low-birth-weight infants. AIM: The aim of this study was to evaluate the influence of periodontal infection as a possible risk factor for preterm low birth weight (LBW) based on age, literacy, and hemoglobin level of mother. MATERIALS AND METHODS: The observational study was conducted on 200 subjects, which were selected from the free labor ward, District Hospital, Saifai, Etawah, UP, India. Periodontal examinations were performed using the World Health Organization criteria. The periodontal status of the mother was recorded using Community Periodontal Index. RESULTS: For this study, chi-square test was performed to know the effect of variables and to find out the statistical significance of the study. Age of mother shows statistical insignificant association with periodontal disease, whereas literacy of mothers showed statistical significant association with periodontal disease, and periodontal status and hemoglobin levels of the mothers also showed a significant association. CONCLUSION: The prevalence of LBW infants was considerably less in mothers with a healthy periodontium and increased with progressive periodontal disease.

5.
J Med Life ; 13(3): 321-328, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33072203

RESUMO

Dental health plays an imperative role in the general health and well-being of an individual. Terminally ill patients due to a compromised immune response are susceptible to a wide array of oral complications, which may affect their ability to speak and chew, leading to malnutrition. The present study was conducted to evaluate dental health and various oral manifestations in terminally ill patients. One hundred twenty terminally ill patients hospitalized with diseases of the respiratory tract, gastrointestinal tract, circulatory system, liver, and endocrinal disorders were included in the study. The evaluation of oral manifestations and their prevalence was done by a single examiner. The oral health was evaluated according to symptoms exhibited by the patients and clinical presentation. Of the patients included in the study, 78 were male, and 42 were female. All the individuals were adults between 25 to 55 years of age. Out of 120 admitted terminally ill patients, 27 subjects had respiratory diseases, 17 had gastrointestinal disorders, 5 had disorders of the circulatory system, 39 had liver disorders, and 32 had endocrine disorders. A need for added comprehension is mandatory to link the inter-relationships between dentistry and medicine to further perk up the management of the overall health of patients, which will further reinforce the partnership between dental and medical communities.


Assuntos
Saúde Bucal , Doente Terminal , Adulto , Doença , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
6.
J Family Med Prim Care ; 8(11): 3695-3699, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-31803675

RESUMO

BACKGROUND: During the orthodontic treatment, maintenance of periodontal health is of utmost importance; hence, this study was conducted to explore the perception and awareness of patients seeking orthodontic treatment toward maintenance of periodontal health and factors affecting the same. MATERIALS AND METHODS: It was a cross-sectional descriptive questionnaire study conducted among134 patients seeking orthodontic treatment from 16 private clinics in Patna. The study was conducted in the month of June 2019. The city was divided into four directions east, west, north, and south and four clinics were selected from each directions randomly. A close-ended questionnaire was prepared consists of demographic details and questions regarding their perception, awareness, and practice to maintain periodontal health from the start of orthodontic treatment. RESULTS: Majority of study participants {74 (55.22%)} were between the age group of 11 and 15 years. Among all study participants, females {81 (60.45%)} were more than males. It was determined that 112 (83.58%) of patients were using tooth brush and tooth paste/powder for cleaning teeth. There was moderate awareness, negative perception, and fair practice of majority of study participants seeking orthodontic treatment toward maintenance of periodontal health. Awareness of study participants was significantly (P-value ≤ 0.05*) associated with practice. CONCLUSION: There was moderate awareness, negative perception, and fair practice of majority of study participants seeking orthodontic treatment toward maintenance of periodontal health. Education of study participants was significantly associated with awareness and practice regarding maintenance of periodontal health. There is further need to educate the orthodontic patients toward maintenance of periodontal health.

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