[Sorption in the treatment of acute peritonitis (experimental study)]. / Endosorbtsiia pri lechenii ostrogo peritonita (éksperimentalnoe issledovanie).

The data on the effective use of the new sorbent KAY and the carbon sorbent "Volna" in the treatment of acute generalized peritonitis were compared. Endosorption with sorbent KAY was conducted on an experimental model of generalized peritonitis. It produced a favorable effect on the functional morphology of the peritoneum by leveling many morphological signs of general intoxication of the organism and in this way creating the conditions for a favorable outcome of the postoperative period. The studies showed that the use of sorbent KAY in the treatment of acute generalized peritonitis facilitates active restoration of the function of vital organs, significantly raises the efficacy of treatment, and shortens the period of in-patient treatment.

[Clinical value of studying phospholipids in young children with acute pneumonia]. / Klinicheskoe znachenie issledovaniia fosfolipidov pri ostroi tiazhelo protekaiushchei pnevmonii u detei rannego vozrasta.

A study was made of phospholipid metabolism in 268 children aged 1 month to 3 years, who were in a critical condition consequent on acute complicated pneumonia. Unbalance of that type metabolism was revealed. It consisted in intensive accumulation of lysophosphatidylcholine, sphingomyelin in the stroma of red blood cells and in a decrease of their pool in the blood plasma as well as in a reduction of the content of phosphatidylserine and phosphatidylethanolamine towards the plasma pool. The bronchial secretion was established to have an elevated content of malonic dialdehyde, diene conjugates and active phospholipases. The indicated membrane destabilizing processes occurring in patients with acute complicated pneumonia, who are in urgent conditions, dictate the necessity of including antioxidants and membrane stabilizers into the multimodality treatment of the disease.

[State of lipid peroxidation system and antioxidant defense in acute respiratory viral infection in children and the principles of pathogenetic therapy]. / Sostaianie sistemy perekisnoe okislenie lipidov--antioksidantnaia zashchita pri ostroi respiratornoi virusnoi infektsii u detei i printsipy patogeneticheskoi terapii.

Summary. Altogether 187 young children presenting with acute respiratory viral infection were examined for lipid peroxidation and antioxidant defense. The principles of the pathogenetically validated antioxidant treatment are discussed.