RESUMO
One hundred and twenty-three female patients aged 16 to 49 years with pulmonary tuberculosis were examined and followed up. Of them, 83 (67.5%) patients in whom tuberculosis had occurred and run in the presence of iron-deficiency anemia (IDA) made up a study group and 40 (32.5%) patients in whom tuberculosis had occurred without IDA formed a control group. In the women from the study group, the clinical manifestations of the disease had its own peculiarities: a less pronounced temperature reaction, meager expectoration, severe signs of hypoxia (dyspnea), and chest pain and 97% were found to have abnormally shaped red blood cells (poikilocytosis). Inclusion of Tardiferon into complex treatment aids in enhancing the efficiency of treatment for tuberculosis in the presence of IDA, promoting to a greater extent the regression of the clinical manifestations of the disease and the achievement of abacillation than cicatrization.
Assuntos
Anemia Ferropriva/tratamento farmacológico , Antituberculosos/uso terapêutico , Compostos Ferrosos/uso terapêutico , Fertilidade , Mucinas/uso terapêutico , Tuberculose Pulmonar/tratamento farmacológico , Adolescente , Adulto , Anemia Ferropriva/sangue , Anemia Ferropriva/complicações , Preparações de Ação Retardada , Combinação de Medicamentos , Quimioterapia Combinada , Feminino , Seguimentos , Humanos , Ferro/sangue , Pessoa de Meia-Idade , Resultado do Tratamento , Tuberculose Pulmonar/sangue , Tuberculose Pulmonar/complicações , Adulto JovemRESUMO
Highly purified base plates of bacteriophage T4D were obtained from lysate of gene 19 am mutant of this phage by differential centrifugation and sucrose gradient. Base plates were studied by means of high speed sedimentation equilibrium. The molecular weight determined by this method is (6.7 plus or minus 0.2)-10-6.
Assuntos
Colífagos/análise , Proteínas Virais/análise , Centrifugação com Gradiente de Concentração , Vírus de DNA/análise , Genes , Peso Molecular , Mutação , UltracentrifugaçãoAssuntos
Colífagos/análise , Escherichia coli , Proteínas Virais , Centrifugação com Gradiente de Concentração , Desoxirribonucleases , Eletroforese em Gel de Poliacrilamida , Teste de Complementação Genética , Magnésio , Microscopia Eletrônica , Peso Molecular , Morfogênese , Mutação , Conformação Proteica , Ribonucleases , Espectrofotometria Ultravioleta , Temperatura , UltracentrifugaçãoAssuntos
Asma/tratamento farmacológico , Tonsila Palatina/patologia , Tonsilite/complicações , Aerossóis , Asma/etiologia , Asma/patologia , Bicarbonatos/administração & dosagem , Bicarbonatos/uso terapêutico , Criança , Pré-Escolar , Citodiagnóstico , Humanos , Métodos , Cloreto de Sódio/administração & dosagem , Cloreto de Sódio/uso terapêutico , Tonsilite/tratamento farmacológicoRESUMO
A method for isolating bacteriophage T4 base plates from lysates of Escherichia coli B cells infected with the ts mutant in gene 19, ts B31 has been developed. By electrophoresis in polyacrylamide gel with sodium dodecyl sulfate the base plates have been shown to contain five to seven protein components with molecular weights of 36,000, 53,000, 66,000, 81,000, 87,000, and probably about 100,000. Electron microscope studies have demonstrated that base plates may occur in two structural states: in the form of hexagons or stars. Star rays and short fibrils are not radial or elongated and are turned sideways at an angle to the radius. Base plates do not complement in vitro with free tail cores isolated after disintegration of particles of the wild-type bacteriophage.
