[A clinical study of doxycycline slow-release gel on periodontitis chemotherapy].

OBJECTIVE: To observe the effect of Doxycycline slow-release on periodontitis therapy. METHODS: 30 patients with chronic periodontitis were chosen and divided into 2 groups randomly,these cases were given Doxycycline slow-release and Zinciodati Comp solution. PLI,GI,SBI,PD,AL,MD and clinical symptoms were observed before and after taking drug. RESULTS: The indose of PLI,GI,SBI,PD,AL,MD were decreased significantly after the use of Doxycycline slow-release gel (P<0.05),the effects of the Doxycycline was better than Zinciodati Comp solution (P<0.01), no adverse drug side effects were found during trial. CONCLUSION: The use of Doxycycline slow-release gel is one of the safe and effective chemotherapy on periodontitis.