1.
Chem Commun (Camb)
; 55(44): 6229-6232, 2019 May 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31086887
RESUMO
The first example of palladium-catalyzed chelation-assisted C-H olefination of 2-amino biaryls using readily available vinylsilanes as unactivated olefinating reagents has been developed, affording valuable arylated vinylsilane compounds in moderate to excellent yields and with exclusive (E)-selectivities.
2.
Chem Commun (Camb)
; 54(76): 10706-10709, 2018 Sep 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30182108
RESUMO
A palladium-catalyzed ketoxime-chelation-assisted enantioselective C-H olefination of 2-arylcyclohex-2-enone oxime ether with a wide range of olefins as coupling partners was developed. Employing ketoxime ether as an efficient directing group, a variety of axially chiral vinyl arenes was synthesized by Pd(ii)-catalyzed C-H functionalization with excellent enantioselectivities (96 â 99% ee) under mild conditions.