1.
Org Lett
; 15(8): 1878-81, 2013 Apr 19.
Artigo
em Inglês
| MEDLINE
| ID: mdl-23537406
RESUMO
Double C-H activations of C(5)-H and Csp(2)-H of 2-substituted N-vinyl- or arylimidazoles were realized without heteroatom-directing assistance by rhodium(III) catalyst. A subsequent oxidative annulation reaction with alkynes efficiently produced aza-fused heterocycles with high molecular complexity in low to excellent yields.
Assuntos
Alcinos/química , Compostos Heterocíclicos/síntese química , Imidazóis/química , Ródio/química , Catálise , Ciclização , Compostos Heterocíclicos/química , Estrutura Molecular , Oxirredução , Estereoisomerismo
2.
Chem Commun (Camb)
; 47(16): 4784-6, 2011 Apr 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21409282
RESUMO
The first Lewis base-catalysed chemoselective asymmetric N-allylic alkylation of enamides with Morita-Baylis-Hillman carbonates has been developed, which affords multifunctional products in moderate to high enantioselectivity (up to 92% ee).