RESUMO
Alterations in the nasal mucous layer of atrophic rhinitis "Ozaena" patients have been investigated. The vast majority (99%) of these patients were women. Morphological findings in healthy nasal mucosa demonstrated the different functional stages of the glandular tissue cells with the healthy epithelium. On the other hand, nasal mucosal material taken from the patients displayed prominent epithelial deterioration, decrease in and loss of cilia, increase in goblet cells with squamous epithelial metaplasia. A decrease in secretory granules and membrane deterioration in the apical region of the secretory cells was also clearly visible. It is possible to postulate that the ultrastructural changes seen in the secretory and storage cycles of glandular tissue of the nasal mucosa from patients seem to arise as a reaction to the superficial epithelial deterioration of the nasal mucosa together with the resulting deterioration of physiological conditions.
Assuntos
Mucosa Nasal/ultraestrutura , Rinite Atrófica/patologia , Epitélio/ultraestrutura , Feminino , Humanos , Microscopia EletrônicaRESUMO
The present investigations demonstrate in animals (rabbits) the existence of a habituation to the vestibular pendular stimulation comparable to the rotatory habituation by constant angular acceleration. There is no mutual transfer, however, between the two habituations. This confirms that the two modes of stimulation are not equivalent. All the tests have been made by ENG recording in total darkness.